Evidence map›Paper›PMID 40880412›Full record

ArticlePloS one2025

"After reducing alcohol, things now work well at home": Perceived impacts of the Mlambe intervention on alcohol use, relationship dynamics, household economics, and HIV treatment adherence in Malawian couples.

Sarah A Gutin, Nancy Mulauzi, Jane Jere, Cobbener Sungani, Scott Tebbetts, Allison Ruark, James Mkandawire, Amy A Conroy

Abstract read
In one paragraph

Article in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Article
  4. "AIDS care · 2026
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Sarah A GutinDepartment of Community Health Systems, School of Nursing, University of California San Francisco, San Francisco, California, United States of America.ORCID https://orcid.org/0000-0002-7634-1296
Nancy MulauziInvest in Knowledge, Zomba, Malawi.
Jane JereUniversity of California Berkeley, Berkeley, California, United States of America.
Cobbener SunganiInvest in Knowledge, Zomba, Malawi.
Scott TebbettsDivision of Prevention Sciences, School of Medicine, University of California San Francisco, San Francisco, California, United States of America.
Allison RuarkBiological and Applied Health Sciences, Wheaton College, Wheaton, Illinois, United States of America.
James MkandawireInvest in Knowledge, Zomba, Malawi.
Amy A ConroyDivision of Prevention Sciences, School of Medicine, University of California San Francisco, San Francisco, California, United States of America.

Funding

An economic and relationship-strengthening intervention for HIV-affected couples who drink alcohol in Malawi - Administrative SupplementR34AA027983 · NIAAA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CONROY, AMY ANNE · 2019 to 2022
$784k
Couples Advancing Together for Safer Conception (CAT-SC): A couples’-based intervention to improve engagement in sexual and reproductive health services for mobile fisherfolk in KenyaK01MH132435 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Sarah A Gutin · 2023 to 2026
$721k
NIAAA NIH HHS R34 AA027983NIMH NIH HHS K01 MH132435
6 · The paper itself

Abstract

Unhealthy alcohol use is prevalent in sub-Saharan Africa and can worsen poverty, couple relationships, and HIV treatment outcomes. In response, we assessed participant experiences with Mlambe, a pilot study of an economic and relationship-strengthening intervention for couples living with unhealthy alcohol use and HIV. Exit interviews were conducted with a subset of 20 couples who participated in a pilot trial of Mlambe in Zomba, Malawi. A 10-month intervention consisted of financial literacy and couples counseling sessions and incentivized savings accounts. Eligible couples were married, ≥ 18, with at least one partner with unhealthy alcohol use (according to AUDIT-C screen), and currently on antiretroviral therapy (ART). Interviews were recorded, transcribed, translated, and analyzed using dyadic framework analysis. Intervention couples reported that alcohol use caused many problems and that reducing or quitting use brought improvements to their physical and emotional health, and the well-being of their marriages and households. Before Mlambe, couples reported that quarrels about alcohol use were common. After the intervention, couples reported improvements to their relationships and less alcohol use, which led to more open and respectful couple communication and other marital improvements including increased sexual satisfaction and trust. Women and men described that post-intervention, men reduced spending on alcohol which improved availability of money for household needs such as food and clothing, and that feeling more economically secure reduced stress and led to a more "peaceful family." After Mlambe, male drinkers described more motivation to pursue income-generating activities, and that reduced alcohol use led to greater medication adherence as they no longer forgot to take ART when drinking. Mlambe may contribute to positive change for couple relationships and health behaviors through mechanisms including reduced conflict and poverty related to reduced alcohol use. The model appears promising for couples in resource-poor settings where HIV, poverty, and alcohol use are mutually reinforcing.

Indexed as

Alcohol DrinkingHIV InfectionsAdultFamily CharacteristicsFemaleHumansMalawiMaleMiddle AgedPilot Projects

Identifiers

PMID40880412
PMCPMC12396686

What Socratic holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.