ReviewFrontiers in nutrition2025
Functional foods and exercise in breast cancer: epigenetic modulation, chemotherapy tolerance, and fatigue management.
Review in Frontiers in nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- The Impact of Diet on Long-Term Oncological Outcomes: Investigating Nutritional Mechanisms in Cancer Prevention Management and Prognosis.Nutrients · 2026Review
- Advances in polyphenol-based strategies for musculoskeletal recovery and exercise rehabilitation in cancer: Mechanistic insights into Wnt/β-catenin and PI3K/Akt signaling pathways and inflammatory markers.Frontiers in oncology · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Breast cancer (BC) is the most commonly diagnosed malignancy among women worldwide. There is increasing interest in the role of modifiable lifestyle factors, particularly nutrition and physical activity, in influencing cancer risk, progression, and treatment response. Objective: This review explores how functional foods and exercise can modulate BC through molecular and epigenetic mechanisms and evaluates their potential as adjunctive strategies in prevention and therapy. Findings: Functional foods, such as those rich in polyphenols, omega-3 fatty acids, vitamins, and probiotics, impact BC biology through DNA methylation, histone modification, and microRNA regulation. Exercise similarly modulates key pathways related to inflammation, immune function, hormone balance, and apoptosis. Combined interventions show synergistic potential in reducing tumor growth, enhancing therapy response, and improving quality of life. Conclusion: Functional foods and exercise represent promising, non-toxic strategies for modulating BC risk and progression via epigenetic and cellular pathways. However, more clinical trials are needed to define optimal combinations and dosages. Future research should focus on precision-based, lifestyle-integrated cancer care approaches.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.