Evidence mapPaperPMID 40880916Full record

ArticleFrontiers in public health2025

Demonstrating public health impacts of translational science at the clinical and translational science collaborative (CTSC) of northern Ohio: a mixed-methods approach using the translational science benefits model.

Lixin Zhang, Umut A Gurkan, Kelli Qua, Shannon Swiatkowski, Sheree Hemphill, Clara M Pelfrey

Abstract read
In one paragraph

Article in Frontiers in public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Embracing complexity: An opportunity for developmental evaluation.Journal of clinical and translational science · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Lixin ZhangClinical and Translational Science Collaborative of Northern Ohio, Case Western Reserve University School of Medicine, Cleveland, OH, United States.
Umut A GurkanDepartment of Mechanical and Aerospace Engineering, Case School of Engineering, Case Western Reserve University, Cleveland, OH, United States.
Kelli QuaCenter for Medical Education, Case Western Reserve University School of Medicine, Cleveland, OH, United States.
Shannon SwiatkowskiClinical and Translational Science Collaborative of Northern Ohio, Case Western Reserve University School of Medicine, Cleveland, OH, United States.
Sheree HemphillClinical and Translational Science Collaborative of Northern Ohio, Case Western Reserve University School of Medicine, Cleveland, OH, United States.
Clara M PelfreyClinical and Translational Science Collaborative of Northern Ohio, Case Western Reserve University School of Medicine, Cleveland, OH, United States.

Funding

Clinical and Translational Science Collaborative of Northern Ohio, Catalyzing Linkages for Everyone's Health (CLE Health)UM1TR004528 · CASE WESTERN RESERVE UNIVERSITY · 2025 to 2025
$7.9M
NCATS NIH HHS UM1 TR004528
6 · The paper itself

Abstract

The Clinical and Translational Science Award (CTSA) program, funded by the National Center for Advancing Translational Sciences (NCATS), aims to accelerate the translation of research into public health impacts. However, measuring the societal impact of translational research poses challenges due to extended timelines for implementation. This study uses the Translational Science Benefits Model (TSBM) to evaluate the societal impact of CTSA-supported research at the Clinical and Translational Science Collaborative (CTSC) of Northern Ohio at Case Western Reserve University (CWRU). Using the TSBM, we asked how investigators have used the CTSC to demonstrate translational science impacts in public health practice both domestically and internationally. Using a mixed methods approach, this study analyzed TSBM-based survey data from CTSC-supported KL2 Scholars and Pilot Program awardees, along with key publications and interviews, to document societal benefits across four TSBM domains: Clinical & Medical, Community & Public Health, Economic, and Policy & Legislative. Findings demonstrate that CTSC-supported research improved public health by enhancing healthcare access, improving health outcomes, informing policy, and generating economic benefits. These impacts span local, national, and global contexts. By applying a mixed methods approach, we demonstrate the value of using the TSBM not just as an evaluative framework, but as a strategic tool for capturing the real-world significance of translational science. This approach strengthens the ability of CTSA hubs to highlight the broader public value of their work, reinforcing the CTSA program's mission to transform scientific discoveries into lasting health and societal benefits.

Indexed as

Public HealthTranslational Research, BiomedicalTranslational Science, BiomedicalCooperative BehaviorHumansOhioSurveys and Questionnairesimpact evaluationmixed method researchpolicypublic healthtranslational sciencetranslational science benefits model (TSBM)translational science case studies

Identifiers

PMID40880916
PMCPMC12380759

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.