Evidence mapPaperPMID 40880952Full record

ArticlePollutants2025

Combined Effect of per- and Polyfluoroalkyl Substances, Toxic Metals, and Essential Elements on Chronic Kidney Disease.

Issah Haruna, Emmanuel Obeng-Gyasi

Abstract read
In one paragraph

Article in Pollutants, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. An Exploration of Machine Learning Methods in Human Biomonitoring.International journal of environmental research and public health · 2026
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Issah HarunaDepartment of Built Environment, North Carolina A&T State University, Greensboro, NC 27411, USA.
Emmanuel Obeng-GyasiDepartment of Built Environment, North Carolina A&T State University, Greensboro, NC 27411, USA.ORCID 0000-0003-3195-706X

Funding

The Impact of Combined Exposure to Metals and Per- and Polyfluoroalkyl Substances on Stress, Cardiovascular Disease Risk and MortalityR16GM149473 · NORTH CAROLINA AGRI & TECH ST UNIV · 2025 to 2025
$142k
NIGMS NIH HHS R16 GM149473
6 · The paper itself

Abstract

Chronic kidney disease (CKD) is a noteworthy global health issue affecting 10% of the world's populace. It is increasingly linked to environmental exposures; however, the interplay of toxic metals, per- and polyfluoroalkyl substances (PFAS), and essential elements has not been fully elucidated. This cross-sectional study analyzed 5800 out of the 9245 participants from the 2017-2018 NHANES dataset to evaluate the combined effect of PFAS, essential elements, and toxic metals on CKD using logistic regression and advanced environmental mixture models, namely, Bayesian Kernel Machine Regression (BKMR), quantile g-computation (qgcomp), and Weighted Quantile Sum (WQS) regression. Our results showed cadmium (Cd) emerging as a significant contributor to CKD (OR = 2.16,

Indexed as

Bayesian Kernel Machine Regressionchronic kidney diseaseenvironmental mixturesessential elementsper- and polyfluoroalkyl substancestoxic metalsWeighted Quantile Sum

Identifiers

PMID40880952
PMCPMC12383139

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.