ReviewWorld journal of clinical pediatrics2025
Recent advances in research on gene polymorphisms in Kawasaki disease.
Review in World journal of clinical pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Kawasaki Disease: Unraveling Immunopathogenesis, Genetic Factors, and AI Applications in Diagnosis with a Focus on Iran.Pediatric cardiology · 2026Review
- The Autophagy-Inflammasome Axis as a Molecular Switch: From Persistent Inflammation to Vascular Remodeling in IVIG-Resistant Kawasaki Disease.International journal of molecular sciences · 2026Review
- Hepatobiliary involvement in Kawasaki disease: from cholestatic hepatitis to the hepatic vascular-biliary unit hypothesis-a state-of-the-art review.Frontiers in immunology · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Kawasaki disease (KD) is a systemic vasculitis primarily affecting children, and represents a major cause of acquired heart disease in this population. Although the etiology of KD remains incompletely understood, existing genome-wide association studies and genome-wide linkage studies have uncovered various susceptibility genes and their associated chromosomal regions as closely related to the onset and progression of KD. With the rapid advancement of high-throughput DNA sequencing technology, an increasing amount of genomic information pertinent to KD has been discovered, offering new perspectives to investigate the pathogenesis of KD. In particular, genetic polymorphisms play a pivotal role in the immune response, coronary artery lesions, and treatment responsiveness in KD, providing fresh insights into optimizing diagnostic and therapeutic strategies. This article aimed to review and summarize the crucial role of genetic polymorphisms in the pathogenesis of KD, analyze the latest advancements in current research, and discuss the potential applications of gene polymorphism studies in the future diagnosis and treatment of KD.
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What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.