Evidence map›Paper›PMID 40881263›Full record

ArticleMed-X2024

Perspectives on non-genetic optoelectronic modulation biointerfaces for advancing healthcare.

Aman Majmudar, Saehyun Kim, Pengju Li, Bozhi Tian

Abstract read
In one paragraph

Article in Med-X, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Aman MajmudarThe James Franck Institute, The University of Chicago, Chicago, IL 60637, USA.
Saehyun KimDepartment of Chemistry, The University of Chicago, Chicago, IL 60637, USA.
Pengju LiPritzker School of Molecular Engineering, The University of Chicago, Chicago, IL 60637, USA.
Bozhi TianThe James Franck Institute, The University of Chicago, Chicago, IL 60637, USA.ORCID 0000-0003-0593-0023

Funding

Multi-site photostimulation devices using porosity-based semiconductor heterojunctions for cardiac resynchronization therapyR01EB036091 · NIBIB · UNIVERSITY OF CHICAGO · PI Narutoshi Hibino, Bozhi Tian · 2024 to 2026
$1.8M
NIBIB NIH HHS R01 EB036091
6 · The paper itself

Abstract

Advancements in optoelectronic biointerfaces have revolutionized healthcare by enabling targeted stimulation and monitoring of cells, tissues, and organs. Photostimulation, a key application, offers precise control over biological processes, surpassing traditional modulation methods with increased spatial resolution and reduced invasiveness. This perspective highlights three approaches in non-genetic optoelectronic photostimulation: nanostructured phototransducers for cellular stimulation, micropatterned photoelectrode arrays for tissue stimulation, and thin-film flexible photoelectrodes for multiscale stimulation. Nanostructured phototransducers provide localized stimulation at the cellular or subcellular level, facilitating cellular therapy and regenerative medicine. Micropatterned photoelectrode arrays offer precise tissue stimulation, critical for targeted therapeutic interventions. Thin-film flexible photoelectrodes combine flexibility and biocompatibility for scalable medical applications. Beyond neuromodulation, optoelectronic biointerfaces hold promise in cardiology, oncology, wound healing, and endocrine and respiratory therapies. Future directions include integrating these devices with advanced imaging and feedback systems, developing wireless and biocompatible devices for long-term use, and creating multifunctional devices that combine photostimulation with other therapies. The integration of light and electronics through these biointerfaces paves the way for innovative, less invasive, and more accurate medical treatments, promising a transformative impact on patient care across various medical fields.

Indexed as

BioelectronicsCardiac pacemakerNeuromodulationPersonalized healthcarePhotostimulation

Identifiers

PMID40881263
PMCPMC12382441

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.