Evidence map›Paper›PMID 40881815›Full record

ArticleJournal of extracellular biology2025

Extracellular Vesicles From Fungal Infection in Humans: A Key Player in Immunological Responses.

Caroline P de Rezende, Patrick W S Santos, Renan A Piraine, Virgínia C Silvestrini, Julio C J Barbosa, Fabiana C P Valera, Edwin Tamashiro, Guilherme G Podolski-Gondim, Silvana M Quintana, Rodrigo Calado and 4 more

Abstract read
In one paragraph

Article in Journal of extracellular biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Biomolecular Corona Remodelling ofJournal of extracellular biology · 2026
    Article
  3. Review
  4. Article
  5. Review
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Caroline P de RezendeDepartment of Biochemistry and Immunology, Ribeirao Preto Medical School University of Sao Paulo Ribeirao Preto São Paulo Brazil.
Patrick W S SantosDepartment of Biochemistry and Immunology, Ribeirao Preto Medical School University of Sao Paulo Ribeirao Preto São Paulo Brazil.
Renan A PiraineDepartment of Biochemistry and Immunology, Ribeirao Preto Medical School University of Sao Paulo Ribeirao Preto São Paulo Brazil.
Virgínia C SilvestriniDepartment of Biochemistry and Immunology, Ribeirao Preto Medical School University of Sao Paulo Ribeirao Preto São Paulo Brazil.
Julio C J BarbosaDepartment of Organic Chemistry, Institute of Chemistry University of Campinas Campinas São Paulo Brazil.
Fabiana C P ValeraDepartment of Otolaryngology, Ribeirao Preto Medical School University of Sao Paulo Ribeirao Preto São Paulo Brazil.
Edwin TamashiroDepartment of Otolaryngology, Ribeirao Preto Medical School University of Sao Paulo Ribeirao Preto São Paulo Brazil.
Guilherme G Podolski-GondimDivision of Neurosurgery Ribeirao Preto Medical School, Department of Surgery and Anatomy University of Sao Paulo Ribeirao Preto São Paulo Brazil.
Silvana M QuintanaDepartment of Gynecology and Obstetrics, Ribeirao Preto Medical School University of Sao Paulo Ribeirao Preto São Paulo Brazil.
Rodrigo CaladoDepartment of Medical Imaging, Hematology and Oncology, Ribeirao Preto Medical School University of Sao Paulo Ribeirao Preto São Paulo Brazil.
Roberto MartinezDepartment of Internal Medicine, Ribeirao Preto Medical School University of Sao Paulo Ribeirao Preto São Paulo Brazil.
Taicia P FillDepartment of Organic Chemistry, Institute of Chemistry University of Campinas Campinas São Paulo Brazil.
Márcio L RodriguesInstitute Carlos Chagas (ICC) Fundacao Oswaldo Cruz (FIOCRUZ) Curitiba Brazil.
Fausto AlmeidaDepartment of Biochemistry and Immunology, Ribeirao Preto Medical School University of Sao Paulo Ribeirao Preto São Paulo Brazil.ORCID https://orcid.org/0000-0002-3782-3698

Funding

An extracellular vesicle component as a candidate to control cryptococcosis.R01AI183314 · NIAID · FUNDACAO OSWALDO CRUZ · PI JOSHUA D NOSANCHUK, Marcio Lourenco Rodrigues · 2024 to 2026
$380k
NIAID NIH HHS R01 AI183314
6 · The paper itself

Abstract

Fungal infections cause approximately 1.6 million deaths annually. Diagnosing and treating fungal infections is difficult due to limited access to diagnostic tests and rising antifungal resistance. Extracellular vesicles (EVs) facilitate interactions between fungal cells and hosts, significantly influencing the pathogen-host relationship. Owing to the complexity of fungal EVs and the lack of clinical studies on their roles in human infections, we analysed EVs from serum and urine samples of patients with infections caused by

Indexed as

clinical samplesextracellular vesicles (EVs)fungal metabolitesimmunomodulationsystemic mycoses

Identifiers

PMID40881815
PMCPMC12381960

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.