Evidence map›Paper›PMID 40881918›Full record

ArticleCureus2025

Prevalence of Metabolic Syndrome and Its Associated Factors Among Malagasy Patients With Ischemic Stroke: A Cross-Sectional Study.

Sitraka Angelo Raharinavalona, Rija Eric Raherison, Thierry Razanamparany, Zo Andrianina Rahobiarivony, Dave Patrick Rakotomalala

Abstract read
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sitraka Angelo RaharinavalonaEndocrinology Department, Soavinandriana Hospital Center, Antananarivo, MDG.
Rija Eric RaherisonEndocrinology Department, Joseph Raseta Befelatanana University Hospital Center, Antananarivo, MDG.
Thierry RazanamparanyEndocrinology Department, Joseph Raseta Befelatanana University Hospital Center, Antananarivo, MDG.
Zo Andrianina RahobiarivonyEndocrinology Department, Soavinandriana Hospital Center, Antananarivo, MDG.
Dave Patrick RakotomalalaEndocrinology Department, Joseph Raseta Befelatanana University Hospital Center, Antananarivo, MDG.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction Metabolic syndrome (MetS) and ischemic stroke are significant public health issues due to their high prevalence and impact on morbidity and mortality. The objective of this study was to determine the prevalence of MetS and its associated factors among Malagasy patients with ischemic stroke. Materials and methods This cross-sectional study was conducted over a three-year period at the Soavinandriana Hospital Center, Antananarivo, Madagascar. MetS was defined according to the International Diabetes Federation's 2009 criteria. Ischemic stroke was confirmed by brain computerized tomography. The TOAST classification was used to determine the etiologies. Results We included 307 patients with ischemic stroke. The prevalence of MetS was 77.9%. According to the logistic regression analysis, the factors associated with MetS were female gender (adjusted odds ratio (aOR) = 3.99, p-value = 0.0031), hypertension (aOR = 4.02, p-value = 0.0029), overweight or obesity (aOR = 2.13, p-value = 0.0122), diabetes (aOR = 4.20, p-value = 0.0011), Glasgow scale ≤10 (aOR = 2.18, p-value = 0.0157), National Institutes of Health Stroke Scale (NIHSS) ≥15 (aOR = 2.94, p-value = 0.0086), and modified Rankin scale ≥ 3 (aOR = 2.29, p-value = 0.0033). As components of MetS, elevated blood pressure was significantly associated with overweight or obesity (aOR = 1.97, p-value = 0.0440), large artery atherosclerosis (LAA) (aOR = 10.2, p-value = 0.0256), and cardioembolism (aOR = 0.25, p-value = 0.0177). The associations between elevated fasting glucose and LAA (aOR = 2.26, p-value = 0.0012) and cardioembolism (aOR = 0.34, p-value = 0.0004). Elevated triglycerides was associated significantly with diabetes (aOR = 2.01, p-value = 0.0452), cardioembolism (aOR = 0.45, p-value = 0.0115), and lacunar infarcts (aOR = 3.05, p-value = 0.0336). Conclusion Screening for MetS should be a routine part of assessing patients with ischemic stroke. Proper management of MetS and its components could lead to improvements in the profile and prognosis of ischemic stroke.

Indexed as

associated factorscardiovascular risk factorsischemic strokemadagascarmetabolic syndrome

Identifiers

PMID40881918
PMCPMC12381903

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.