Evidence map›Paper›PMID 40882811›Full record

ArticleJournal of advanced research2026

The therapeutic value of "Bile Transfer" for complications of acute pancreatitis: A retrospective clinical study.

Liang Zhang, Zijian Huang, Yusen Feng, Menglu Yang, Hongtao Li, Jinbo Huang, Baiqiang Lin, Zhengtian Li, Gang Wang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of advanced research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Liang ZhangDepartment of Oncology and Laparoscopy Surgery, The First Affiliated Hospital of Harbin Medical University, 150000 Harbin, Heilongjiang Province, China; Key Laboratory of Hepatosplenic Surgery, Ministry of Education, The First Affiliated Hospital of Harbin Medical University, 150000 Harbin, Heilongjiang Province, China.
Zijian HuangDepartment of Oncology and Laparoscopy Surgery, The First Affiliated Hospital of Harbin Medical University, 150000 Harbin, Heilongjiang Province, China; Key Laboratory of Hepatosplenic Surgery, Ministry of Education, The First Affiliated Hospital of Harbin Medical University, 150000 Harbin, Heilongjiang Province, China.
Yusen FengDepartment of Oncology and Laparoscopy Surgery, The First Affiliated Hospital of Harbin Medical University, 150000 Harbin, Heilongjiang Province, China; Key Laboratory of Hepatosplenic Surgery, Ministry of Education, The First Affiliated Hospital of Harbin Medical University, 150000 Harbin, Heilongjiang Province, China.
Menglu YangDepartment of Pancreatic and Biliary Surgery, The First Affiliated Hospital of Harbin Medical University, 150000 Harbin, Heilongjiang Province, China.
Hongtao LiDepartment of Oncology and Laparoscopy Surgery, The First Affiliated Hospital of Harbin Medical University, 150000 Harbin, Heilongjiang Province, China; Key Laboratory of Hepatosplenic Surgery, Ministry of Education, The First Affiliated Hospital of Harbin Medical University, 150000 Harbin, Heilongjiang Province, China.
Jinbo HuangDepartment of Oncology and Laparoscopy Surgery, The First Affiliated Hospital of Harbin Medical University, 150000 Harbin, Heilongjiang Province, China.
Baiqiang LinDepartment of Oncology and Laparoscopy Surgery, The First Affiliated Hospital of Harbin Medical University, 150000 Harbin, Heilongjiang Province, China.
Zhengtian LiDepartment of Oncology and Laparoscopy Surgery, The First Affiliated Hospital of Harbin Medical University, 150000 Harbin, Heilongjiang Province, China. Electronic address: 601059@hrbmu.edu.cn.
Gang WangDepartment of Oncology and Laparoscopy Surgery, The First Affiliated Hospital of Harbin Medical University, 150000 Harbin, Heilongjiang Province, China; Key Laboratory of Hepatosplenic Surgery, Ministry of Education, The First Affiliated Hospital of Harbin Medical University, 150000 Harbin, Heilongjiang Province, China. Electronic address: wgilu79@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAcute pancreatitis (AP) is one of the most common gastrointestinal diseases, imposing a significant burden on patients, with its incidence steadily increasing worldwide. Despite a drop in fatality rates, AP-related complications remain high, impacting prognosis.

objectivesThis retrospective clinical study introduces the concept of "bile transfer" (BT) and explores its potential in reducing AP-related complications.

methodsThis single-center, retrospective cohort study evaluated 344 AP patients with gallbladder distension at our hospital from January 2019 to December 2024. Patients were classified into three groups: percutaneous transhepatic gallbladder drainage (PTGD) + bile reinfusion (BT group), PTGD-alone, and conventional treatment to assess complication rates. Logistic regression identified independent risk factors for treatment outcomes. Restricted cubic splines (RCS) were employed to identify optimal indications for BT.

resultsAmong the 344 patients, the incidence of new complications in the BT group was 21.50 %, significantly lower than in the PTGD-alone (46.59 %) and conventional treatment groups (54.36 %) (p < 0.001). Logistic regression identified Total bilirubin (TBIL), Ca

conclusionThis study introduces BT and shows that PTGD combined with bile reinfusion significantly reduces complications in AP patients. We identified optimal indications and predictors for BT. These findings are clinically important for improving AP patient prognosis.

Indexed as

BileDrainagePancreatitisAcute DiseaseAdultAgedFemaleHumansMaleMiddle AgedPrognosisRetrospective StudiesRisk FactorsTreatment OutcomeAcute pancreatitisBile reinfusionBile transferComplicationsPercutaneous transhepatic gallbladder drainage

Identifiers

PMID40882811
PMCPMC13131511

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.