Evidence map›Paper›PMID 40883676›Full record

ArticleBMC geriatrics2025

The Caribbean American Dementia and Aging Study: protocol for a population-based study of older adult health and dementia in Cuba, the Dominican Republic, and Puerto Rico.

Mao-Mei Liu, Jorge Llibre-Guerra, Chris Soria, Jing Li, Tania Zayas Llerena, Guillermina Rodriguez, Daisy Acosta, Ivonne Jiménez Velázquez, Juan J Llibre-Rodriguez, William H Dow

Abstract read
In one paragraph

Article in BMC geriatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Mao-Mei LiuDepartment of Demography, University of California at Berkeley, Berkeley, USA. mao-mei_liu@berkeley.edu.
Jorge Llibre-GuerraDepartment of Neurology, School of Medicine, Washington University in St. Louis, St. Louis, USA.
Chris SoriaDepartment of Demography, University of California at Berkeley, Berkeley, USA.
Jing LiDepartment of Pharmacy, University of Washington, Seattle, USA.
Tania Zayas LlerenaDementia Research Unit, Medical University of Havana, Havana, Cuba.
Guillermina RodriguezUniversidad Nacional Pedro Henríquez Ureña (UNPHU), Santo Domingo, Dominican Republic.
Daisy AcostaUniversidad Nacional Pedro Henríquez Ureña (UNPHU), Santo Domingo, Dominican Republic.
Ivonne Jiménez VelázquezSchool of Medicine, University of Puerto Rico, San Juan, Puerto Rico.
Juan J Llibre-RodriguezDementia Research Unit, Medical University of Havana, Havana, Cuba.
William H DowDepartment of Demography, University of California at Berkeley, Berkeley, USA. wdow@berkeley.edu.

Funding

Dementia Determinants in Caribbean and U.S. HispanicsR01AG064778 · NIA · UNIVERSITY OF CALIFORNIA BERKELEY · PI DOW, WILLIAM H. · 2019 to 2023
$3.6M
Understanding Alzheimer disease heterogeneity in Hispanic populations.K01AG073526 · NIA · WASHINGTON UNIVERSITY · PI Jorge Jesus Llibre-Guerra · 2022 to 2026
$511k
NIA NIH HHS K01 AG073526NIA NIH HHS R01 AG064778NIH HHS R01AG064778
6 · The paper itself

Abstract

backgroundThe Hispanic Caribbean region is rapidly aging but national population-based aging surveys are rare. The Caribbean American Dementia and Aging Study (CADAS) is a multi-purpose household study of aging with a particular focus on the life course determinants and consequences of health and dementia in three countries with many similarities but divergent recent histories: Puerto Rico, Dominican Republic, and Cuba.

methodsCADAS will survey population-based samples of adults ages 65 and over. In Puerto Rico and Dominican Republic these will be nationally representative samples of 1,500 adults each; the Cuban survey will include 1,500 adults from purposively selected urban and rural areas. We are collecting detailed data modules that encompass individual health metrics, sociodemographic background, physical and neurological exam, cognitive function, and household economic status. Data modules are generally harmonized with related Health and Retirement Surveys (HRS) around the world. Participant cognitive assessment protocols and informant reports were designed to be broadly harmonized with the 10/66 Dementia Research Group assessments and the Harmonized Cognitive Assessment Protocol (HCAP). Data collection is in progress in all three countries. For a subset of CADAS data, clinicians will provide online clinical consensus diagnoses based on National Institute on Aging and Alzheimer’s Association (NIA-AA) ratings. DISCUSSION: With this study, we will contribute nationally representative data on health, dementia and cognitive aging in Dominican Republic and Puerto Rico, as well as harmonized data in Cuba to expand understanding of aging and dementia in the Hispanic Caribbean and promote cross-national comparative research around the world.

Indexed as

AgingDementiaHealth StatusPopulation SurveillanceAgedAged, 80 and overCaribbean PeopleCubaDominican RepublicFemaleHumansMalePuerto RicoAgingAlzheimer’s diseaseCaribbeanCubaDementiaDominican RepublicInternational comparisonPopulation-based studiesPopulation healthPuerto Rico

Identifiers

PMID40883676
PMCPMC12395809

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.