Evidence map›Paper›PMID 40884529›Full record

ReviewEpilepsia2025

Deciphering SCN2A: A comprehensive review of rodent models of Scn2a dysfunction.

Katelin E J Scott, Maria Fernanda Hermosillo Arrieta, Aislinn J Williams

Abstract readReview
In one paragraph

Review in Epilepsia, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Katelin E J ScottInterdisciplinary Neuroscience Graduate Program, University of Iowa, Iowa City, Iowa, USA.ORCID https://orcid.org/0000-0002-1574-2838
Maria Fernanda Hermosillo ArrietaIowa Neuroscience Institute, University of Iowa, Iowa City, Iowa, USA.ORCID https://orcid.org/0009-0002-9309-401X
Aislinn J WilliamsIowa Neuroscience Institute, University of Iowa, Iowa City, Iowa, USA.

Funding

NEUROSCIENCE TRAINING PROGRAMT32NS007421 · NINDS · UNIVERSITY OF IOWA · PI Sheila A Baker, Daniel T. Tranel · 1999 to 2026
$6.0M
Iowa-Diversifying Research And Mentorship (iDREAM)R25NS130966 · NINDS · UNIVERSITY OF IOWA · PI Rainbo Hultman, Daniel T. Tranel · 2023 to 2026
$1.4M
NINDS NIH HHS R25 NS130966NINDS NIH HHS T32 NS007421Roy J. and Lucille A. Carver College of Medicine, University of Iowa Roy J. Carver TrustU.S. Department of Defense DOD AR220030
6 · The paper itself

Abstract

SCN2A encodes for the alpha subunit of the voltage-gated sodium channel Na

Indexed as

Disease Models, AnimalEpilepsyNAV1.2 Voltage-Gated Sodium ChannelAnimalsHumansMiceNAV1.2 Voltage-Gated Sodium ChannelSCN2A protein, humanautismepilepsyNav1.2therapeutics

Identifiers

PMID40884529
PMCPMC12779317

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.