Evidence map›Paper›PMID 40885758›Full record

ArticleScientific reports2025

Characterization of cervical fluid Ureaplasma species in pregnant women with spontaneous preterm delivery.

Radka Bolehovska, Antonin Libra, Rudolf Kukla, Pavel Bostik, Ivana Musilova, Jana Matulova, Mariusz Grzesiak, Bo Jacobsson, Marian Kacerovsky

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Radka Bolehovska *Institute of Clinical Microbiology, University Hospital, Hradec Kralove, Czech Republic.
Antonin Libra *Biomedical Research Center, University Hospital Hradec Kralove, Hradec Kralove, Czech Republic.
Rudolf KuklaInstitute of Clinical Microbiology, University Hospital, Hradec Kralove, Czech Republic.
Pavel BostikInstitute of Clinical Microbiology, University Hospital, Hradec Kralove, Czech Republic.
Ivana MusilovaInstitute of Clinical Microbiology, Faculty of Medicine in Hradec Kralove, Charles University, Hradec Kralove, Czech Republic.
Jana MatulovaDepartment of Non-Medical Studies, Faculty of Medicine in Hradec Kralove, Charles University, Hradec Kralove, Czech Republic.
Mariusz GrzesiakDepartment of Perinatology, Obstetrics and Gynecology, Polish Mother's Memorial Hospital, Lodz, Poland.
Bo JacobssonDepartment of Perinatology, Obstetrics and Gynecology, Institute of Clinical Science, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Marian KacerovskyInstitute of Clinical Microbiology, Faculty of Medicine in Hradec Kralove, Charles University, Hradec Kralove, Czech Republic. marian.kacerovsky@fnol.cz.

Funding

University Hospital Hradec Kralove, Czech Republic A long-term developmental plan.University Hospital Hradec Kralove, Hradec Králové, Czech Republic. the Biomedical Indicators for Personalized Medicine project (BIPOLE), project ID CZ.02.01.01/00/23_021/0008439]
6 · The paper itself

Abstract

Ureaplasma spp., commonly identified in the vagina/cervix of pregnant women with spontaneous preterm delivery, are the most frequently detected microorganisms in amniotic fluid. To date, 14 U. spp. serotypes have been characterized; however, modern molecular biology methods can distinguish different U. spp genotypes. Considering these factors, a knowledge gap exists regarding the association between U. spp. genotypes and the risk of the ascension of U. spp. from the cervix to the amniotic cavity. To fill this gap, an expanded multilocus sequence-typing scheme of U. spp. was performed to assess the relationship between cervical and amniotic fluid U. spp. in pregnant women with spontaneous preterm delivery. This study included 109 and 69 pregnant women with spontaneous preterm labor (PTL) and preterm prelabor rupture of membranes (PPROM), respectively. U. spp. DNA in cervical fluid was identified in 49% and 55% of the women with PTL and PPROM, respectively. The concurrent presence of U. spp. DNA in amniotic fluid was observed in 17% and 59% of the pregnant women with PTL and PPROM, respectively. Among pregnant women with PTL and PPROM, 38 expanded sequence types of cervical U. spp. were identified. No associations were observed between specific genotypes, subgroups, or clusters of cervical U. spp. and the presence of amniotic fluid U. spp. in pregnant women with spontaneous preterm delivery.

Indexed as

Cervix UteriPremature BirthUreaplasmaUreaplasma InfectionsAdultAmniotic FluidDNA, BacterialFemaleGenotypeHumansMultilocus Sequence TypingObstetric Labor, PrematurePregnancyPregnancy Complications, InfectiousPremature Rupture of Fetal MembranesYoung AdultDNA, BacterialAmniotic fluidGenital mycoplasmasInvasive samplingNon-invasive samplingPreterm birth

Identifiers

PMID40885758
PMCPMC12398508

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.