Evidence map›Paper›PMID 40885898›Full record

ArticleBMC pediatrics2025

Association between preoperative neutrophil-to-lymphocyte ratio and length of stay in pediatric patients undergoing laparoscopic appendectomy: a retrospective cohort study.

Ming Liu, Yunpeng Gou, Ping Yang

Abstract read
In one paragraph

Article in BMC pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

3 authors.

Ming LiuDepartment of Pediatric Surgery, Suining Central Hospital, No. 127 of Desheng West Road, Chuanshan District, Suining, Sichuan Province, 629000, China.
Yunpeng GouDepartment of Pediatric Surgery, Suining Central Hospital, No. 127 of Desheng West Road, Chuanshan District, Suining, Sichuan Province, 629000, China.
Ping YangDepartment of Pediatric Surgery, Suining Central Hospital, No. 127 of Desheng West Road, Chuanshan District, Suining, Sichuan Province, 629000, China. 13320245381@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAlthough the neutrophil-to-lymphocyte ratio (NLR) has demonstrated diagnostic utility in appendicitis, its predictive value for postoperative recovery outcomes remains uncertain. This investigation sought to examine the association between preoperative NLR and length of stay (LOS) in pediatric patients who underwent laparoscopic appendectomy.

methodsWe performed a retrospective analysis of 815 pediatric patients (aged < 18 years) who underwent laparoscopic appendectomy between January 2021 and December 2022 at Suining Central Hospital. The primary exposure variable was preoperative NLR, with postoperative LOS serving as the main outcome measure. Multiple regression models were established, with adjustments for demographic characteristics, clinical parameters, and surgical variables.

resultsFollowing comprehensive adjustment, each 10-unit increment in NLR was associated with a 0.19-day prolongation in LOS (95% CI: 0.02, 0.36; P = 0.025). Stratified analyses demonstrated significant positive correlations in male patients, cases without appendiceal fecalith, patients without drainage tubes, and those with uncomplicated appendicitis (all P < 0.05). Smooth curve analysis revealed a consistent positive association between NLR and LOS throughout the entire spectrum of NLR values.

conclusionPreoperative NLR demonstrated a positive association with postoperative LOS in pediatric patients undergoing laparoscopic appendectomy, indicating its potential value as a predictive marker for hospital resource utilization and perioperative management optimization.

Indexed as

AppendectomyAppendicitisLaparoscopyLength of StayLymphocytesNeutrophilsAdolescentChildChild, PreschoolFemaleHumansLeukocyte CountLymphocyte CountMalePredictive Value of TestsPreoperative PeriodLaparoscopic appendectomyLength of stayNeutrophil-to-lymphocyte ratioPediatric appendicitisPostoperative outcomes

Identifiers

PMID40885898
PMCPMC12398991

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.