ReviewAdvances in experimental medicine and biology2025
Circular RNAs in Brain Physiology and Neurologic Diseases.
Review in Advances in experimental medicine and biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Beyond Coding Variants: RNA-Level Mechanisms in Human Disease and Precision Therapeutics.Genes · 2026Review
- From chromatin to proteostasis: multilevel gene regulation in Mendelian diseases.Frontiers in epigenetics and epigenomics · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In the past ten years, advancements in sequencing technology have allowed scientists to study the function and expression of noncoding RNAs (ncRNAs). One particular type of ncRNA, called circular RNAs (circRNAs), are closed loops that are found in large quantities and are evolutionarily conserved across different species. These circRNAs can be derived from both coding and noncoding transcripts and can regulate cellular proteins and sequester microRNAs. In the mammalian brain, circRNAs are more highly expressed compared to other tissues, suggesting their importance in brain function and pathology. However, there is still limited knowledge about circRNAs in brain cells. By gaining a better understanding of their role in neurological pathways, we can fill in the gaps and develop therapeutic approaches for future neurological diseases.
Indexed as
Identifiers
40886288What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.