Evidence map›Paper›PMID 40887103›Full record

ArticleRenal failure2025

Glycyrrhizin alleviates contrast-induced acute kidney injury via inhibiting HMGB1-mediated renal tubular epithelial cells ferroptosis.

Fang-Yuan Tian, Kun Liu, Zhi-Yao Tang, Ge Zhou, Guang-Liang Zhou, Rui-Feng Chen, Hao-Bo Liu, Wei-Jin Fang, Xiao-Cong Zuo, Ling-Yun Zhou

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Renal failure, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Molecules (Basel, Switzerland) · 2026
    Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Fang-Yuan TianDepartment of Pharmacy, The Third Xiangya Hospital, Central South University, Changsha, Hunan Province, China.
Kun LiuDepartment of Pharmacy, The Third Xiangya Hospital, Central South University, Changsha, Hunan Province, China.
Zhi-Yao TangDepartment of Pharmacy, The Third Xiangya Hospital, Central South University, Changsha, Hunan Province, China.
Ge ZhouDepartment of Pharmacy, The Third Xiangya Hospital, Central South University, Changsha, Hunan Province, China.
Guang-Liang ZhouDepartment of Pharmacy, The Third Xiangya Hospital, Central South University, Changsha, Hunan Province, China.
Rui-Feng ChenDepartment of Pharmacy, The Third Xiangya Hospital, Central South University, Changsha, Hunan Province, China.
Hao-Bo LiuDepartment of Pharmacy, The Third Xiangya Hospital, Central South University, Changsha, Hunan Province, China.
Wei-Jin FangDepartment of Pharmacy, The Third Xiangya Hospital, Central South University, Changsha, Hunan Province, China.
Xiao-Cong ZuoDepartment of Pharmacy, The Third Xiangya Hospital, Central South University, Changsha, Hunan Province, China.
Ling-Yun ZhouDepartment of Pharmacy, The Third Xiangya Hospital, Central South University, Changsha, Hunan Province, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Contrast-induced acute kidney injury (CI-AKI) is the third leading cause of AKI, but there are no effective preventive or therapeutic measures in clinical practice. Glycyrrhizin, a bioactive compound isolated from the

Indexed as

Acute Kidney InjuryContrast MediaFerroptosisGlycyrrhizic AcidHMGB1 ProteinAnimalsCell LineDisease Models, AnimalEpithelial CellsHumansIohexolKidney TubulesMaleMiceMice, Inbred C57BLMice, KnockoutContrast MediaGlycyrrhizic AcidHMGB1 ProteinIohexolContrast-induced AKIferroptosisglycyrrhizinHMGB1renal tubular epithelial cells

Identifiers

PMID40887103
PMCPMC12404086

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.