ReviewDiscover oncology2025
Ferroptosis and non-coding RNAs in breast cancer: insights into CAF and TAM interactions.
Review in Discover oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed.
- State-Aware RNA Biomarkers in Triple-Negative Breast Cancer (TNBC): Integrating Tumor Plasticity, Spatial Architecture, and Temporal Monitoring.International journal of molecular sciences · 2026Review
- From Integrated Analysis to Clinical Insight: ncRNA-Mediated Ferroptosis in Glioblastoma.Cancers · 2026Review
- Subtype-Consistent Upregulation of Ferroptosis-Associated Pathways in Breast Cancer with Heterogeneous Prognostic Implications and Systemic Response to Cryoablation.International journal of molecular sciences · 2026Article
- A ferroptosis-related competing endogenous RNA network: HOX transcript antisense intergenic RNA/miR-129-5p/brain and acute leukemia, cytoplasmic axis contributes to the malignant progression of esophageal squamous cell carcinoma.Translational cancer research · 2026Article
- A ResNet-50-UNet Hybrid with Whale Optimization Algorithm for Accurate Liver Tumor Segmentation.Diagnostics (Basel, Switzerland) · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Ferroptosis, a form of regulated cell death characterized by the accumulation of lipid peroxides, has emerged as a crucial player in cancer biology, particularly in breast cancer. This review article explores the intricate regulation of ferroptosis by non-coding RNAs (ncRNAs) within the breast cancer tumor microenvironment (TME). We delve into the mechanisms through which various classes of ncRNAs, including microRNAs, long non-coding RNAs, and circular RNAs, modulate the ferroptotic response in breast cancer cells. Furthermore, we examine the interactions between ferroptosis and the TME, specifically focusing on cancer-associated fibroblasts (CAFs) and tumor-associated macrophages (TAMs). By highlighting the bidirectional relationships between these components, we aim to elucidate how the modulation of ferroptosis by ncRNAs can influence the behavior of CAFs and TAMs, ultimately impacting tumor progression and therapeutic response. This comprehensive overview underscores the potential of targeting ncRNA-mediated regulation of ferroptosis as a novel therapeutic strategy in breast cancer treatment, with implications for enhancing the efficacy of existing therapies and improving patient outcomes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.