Evidence map›Paper›PMID 40888921›Full record

ArticleWorld journal of urology2025

The effect of chronic kidney disease on adverse in-hospital outcomes after partial nephrectomy.

Calogero Catanzaro, Fabian Falkenbach, Andrea Marmiroli, Mattia Longoni, Quynh Chi Le, Michele Nicolazzini, Federico Polverino, Jordan A Goyal, Lorenzo Bianchi, Pietro Piazza and 11 more

Abstract read
PubMed Publisher
In one paragraph

Article in World journal of urology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Calogero CatanzaroCancer Prognostics and Health Outcomes Unit, Division of Urology, University of Montréal Health Center, Montréal, Québec, Canada. calogero.catanzaro@studio.unibo.it.
Fabian FalkenbachCancer Prognostics and Health Outcomes Unit, Division of Urology, University of Montréal Health Center, Montréal, Québec, Canada.
Andrea MarmiroliCancer Prognostics and Health Outcomes Unit, Division of Urology, University of Montréal Health Center, Montréal, Québec, Canada.
Mattia LongoniCancer Prognostics and Health Outcomes Unit, Division of Urology, University of Montréal Health Center, Montréal, Québec, Canada.
Quynh Chi LeCancer Prognostics and Health Outcomes Unit, Division of Urology, University of Montréal Health Center, Montréal, Québec, Canada.
Michele NicolazziniCancer Prognostics and Health Outcomes Unit, Division of Urology, University of Montréal Health Center, Montréal, Québec, Canada.
Federico PolverinoCancer Prognostics and Health Outcomes Unit, Division of Urology, University of Montréal Health Center, Montréal, Québec, Canada.
Jordan A GoyalCancer Prognostics and Health Outcomes Unit, Division of Urology, University of Montréal Health Center, Montréal, Québec, Canada.
Lorenzo BianchiDivision of Urology, IRCCS Azienda Ospedaliero-Universitaria Di Bologna, Bologna, Italy.
Pietro PiazzaDivision of Urology, IRCCS Azienda Ospedaliero-Universitaria Di Bologna, Bologna, Italy.
Matteo DroghettiDivision of Urology, IRCCS Azienda Ospedaliero-Universitaria Di Bologna, Bologna, Italy.
Fred SaadCancer Prognostics and Health Outcomes Unit, Division of Urology, University of Montréal Health Center, Montréal, Québec, Canada.
Shahrokh F ShariatDepartment of Urology, Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria.
Markus GraefenMartini-Klinik Prostate Cancer Center, University Hospital Hamburg- Eppendorf, Hamburg, Germany.
Matteo FerroUniversità Degli Studi Di Milano, Milan, Italy.
Alberto BrigantiVita-Salute San Raffaele University, Milan, Italy.
Felix K H ChunDepartment of Urology, Goethe University Frankfurt, University Hospital, Frankfurt Am Main, Germany.
Alessandro VolpeDivision of Urology, Department of Translational Medicine, University of Eastern Piedmont, Maggiore Della Carità Hospital, Novara, Italy.
Nicola LongoDepartment of Neurosciences, Science of Reproduction and Odontostomatology, University of Naples Federico II, 80131, Naples, Italy.
Riccardo SchiavinaDivision of Urology, IRCCS Azienda Ospedaliero-Universitaria Di Bologna, Bologna, Italy.
Pierre I KarakiewiczCancer Prognostics and Health Outcomes Unit, Division of Urology, University of Montréal Health Center, Montréal, Québec, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionPreoperative chronic kidney disease (CKD) frequently affects patients with renal cell carcinoma undergoing partial nephrectomy (PN). However, the association between CKD and adverse in-hospital outcomes after PN has not been thoroughly investigated.

methodsDescriptive analyses, 1:2 propensity score matching (PSM) and multivariable logistic and Poisson regression models were used within the National Inpatient Sample (2006–2019) PN patients. CKD severity was stratified as mild (stage II) vs. moderate (stage III) vs. severe (stage IV/V).

resultsOf 33,639 PN patients, 3,473 (10.4%) had CKD, classified as mild (1,821, 5.4%), moderate (1,343, 4.0%), and severe (309, 0.9%). In PN patients, overall CKD rate increased from 4.3–14.1% (2006–2019, EAPC: + 7.2%, p < 0.001). Any CKD in PN patients was associated with higher rates of adverse in-hospital outcomes in 14 of 15 categories, including acute kidney injury (+ 26.2%), overall complications (+ 22.6%), and prolonged length of stay (+ 13.5%, all p < 0.001). After detailed multivariable adjustment, any CKD in PN independently predicted higher rates of adverse in-hospital outcomes in 14 of 15 examined categories, with the odds ratio (OR) ranging from 8.13 for dialysis for acute kidney failure, 6.70 for acute kidney injury, and 2.6 for overall complications (all p < 0.001). Similar observations were made in analyses that relied on specific CKD severity (mild, moderate and severe).

conclusionCKD patients invariably exhibited higher rates of adverse in-hospital outcomes after PN. In consequence, they should be given special attention for preoperative optimization, especially when CKD is either moderate or severe.

Indexed as

Carcinoma, Renal CellKidney NeoplasmsNephrectomyPostoperative ComplicationsRenal Insufficiency, ChronicAgedFemaleHumansMaleMiddle AgedRetrospective StudiesSeverity of Illness IndexTreatment OutcomeChronic kidney diseaseComplicationsKidney cancerNISPartial nephrectomy

Identifiers

PMID40888921

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.