Evidence map›Paper›PMID 40888970›Full record

ReviewHernia : the journal of hernias and abdominal wall surgery2025

To infinity and beyond: the promise of data-driven 3D printing of hernia mesh - a primer for surgeons.

Edward Young, James Lawson, Alex Karatassas, Chrys Hensman

Abstract readReview
In one paragraph

Review in Hernia : the journal of hernias and abdominal wall surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Edward YoungDepartment of Surgery, The Queen Elizabeth Hospital, The University of Adelaide, Adelaide, South Australia, Australia. e.young@adelaide.edu.au.ORCID 0000-0002-5262-5200
James LawsonSchool of Engineering, Ulster University, Belfast, Northern Ireland, United Kingdom.ORCID 0009-0003-5664-223X
Alex KaratassasDepartment of Surgery, The Queen Elizabeth Hospital, The University of Adelaide, Adelaide, South Australia, Australia.
Chrys HensmanSwinburne University of Technology, University of Oceania, Melbourne, VIC, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeAbdominal wall hernias account for a substantial operative caseload in general surgery globally. Optimal hernia care should be tailored to individual circumstances. To repair the three-dimensional (3D) abdominal wall, 3D-printed patient-specific implants may be superior to current mesh products. The aim was to review the current state of 3D printing technology in custom hernia mesh production, and its safety and efficacy for tailored hernia care.

methodsA literature search within PubMed and Scopus databases were performed in March 2025, in accordance to PRISMA-ScR framework, using keyword combinations of printing, mesh, hernia, safety, efficacy and their derivatives. Full-text papers relevant to the study aim in all formats and languages were included, and risk of bias assessment was performed. The review was not eligible for registration with PROSPERO. Papers were grouped by general theme, and a narrative synthesis was performed.

resultsThirty relevant papers were identified from 14,210 abstracts. Literature on 3D-printed hernia mesh was sparse, with majority of papers being preclinical. General focus of the literature was production, cellular toxicity, performance of adjuncts and short-term tolerance in small animals. Risk of bias was globally high to critical, due to underreporting of in vitro and in vivo methodology. Safety and clinical efficacy of 3D-printed mesh remained unknown. Numerous issues, including production, sterilisation and regulations, were identified and discussed.

conclusion3D-printed hernia mesh is the next step towards tailored hernia care, with significant potential not otherwise available with traditional mesh products. Substantial research is still required to clarify its safety and efficacy.

Indexed as

Hernia, AbdominalHerniorrhaphyPrinting, Three-DimensionalSurgical MeshHumans3D printingHerniaIndexIntegrationMeshReview

Identifiers

PMID40888970
PMCPMC12401771

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.