Evidence mapPaperPMID 40892155Full record

ArticleEJNMMI research2025

Imaging renal mitochondrial dysfunction in chronic kidney disease: a repurposed role for [

Soo Bin Park, Chae Hong Lim, So-Young Jin, Yon Hee Kim, Haekyung Lee, Hyoungnae Kim, Hyunjin Noh, Jin Seok Jeon, Soon Hyo Kwon

Abstract read
In one paragraph

Article in EJNMMI research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Soo Bin ParkDepartment of Nuclear Medicine, Soonchunhyang University Hospital, Soonchunhyang University College of Medicine, Seoul, Republic of Korea.ORCID http://orcid.org/0000-0002-3502-8818
Chae Hong LimDepartment of Nuclear Medicine, Soonchunhyang University Hospital, Soonchunhyang University College of Medicine, Seoul, Republic of Korea.
So-Young JinDepartment of Pathology, Soonchunhyang University Hospital, Soonchunhyang University College of Medicine, Seoul, Republic of Korea.
Yon Hee KimDepartment of Pathology, Soonchunhyang University Hospital, Soonchunhyang University College of Medicine, Seoul, Republic of Korea.
Haekyung LeeDivision of Nephrology, Department of Internal Medicine, Soonchunhyang University Hospital, Soonchunhyang University College of Medicine, Seoul, Republic of Korea.
Hyoungnae KimDivision of Nephrology, Department of Internal Medicine, Soonchunhyang University Hospital, Soonchunhyang University College of Medicine, Seoul, Republic of Korea.
Hyunjin NohDivision of Nephrology, Department of Internal Medicine, Soonchunhyang University Hospital, Soonchunhyang University College of Medicine, Seoul, Republic of Korea.
Jin Seok JeonDivision of Nephrology, Department of Internal Medicine, Soonchunhyang University Hospital, Soonchunhyang University College of Medicine, Seoul, Republic of Korea.
Soon Hyo KwonDivision of Nephrology, Department of Internal Medicine, Soonchunhyang University Hospital, Soonchunhyang University College of Medicine, Seoul, Republic of Korea. ksoonhyo@schmc.ac.kr.ORCID http://orcid.org/0000-0002-4114-4196

Funding

National Research Foundation of Korea NRF-2020R1G1A1102033National Research Foundation of Korea NRF-2022R1A2C1007571
6 · The paper itself

Abstract

background[

resultsA total of 11 patients with newly diagnosed CKD and 27 matched healthy volunteers underwent [99mTc]Tc-MIBI dynamic renal scans and SPECT/CT. Quantitative analyses of the left kidneys assessed time-activity curves, percentage of renal uptake, and standardized uptake values (SUV). Renal mitochondrial content in CKD patients was evaluated using immunohistochemistry of kidney biopsy samples. CKD patients had comparable eGFR to healthy volunteers but exhibited significantly lower renal [

conclusions[

Indexed as

[99mTc]Tc-MIBIChronic kidney diseaseMIBIMitochondrial dysfunctionSPECT/CT

Identifiers

PMID40892155
PMCPMC12405237

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.