Fabrication and Application of a Microfluidic Chip for Biofilm Cultivation and Analysis under Controlled Flow.

Adei Abouhagger, Eivydas Andriukonis, Goda Grigorianaite, Raiane Rodrigues da Silva, Kamile Kasperaviciute, Arunas Stirke, Wanessa C Ma Melo

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Article in ACS omega, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

Direct Molding of Luer Connections in PDMS Microfluidic Devices: Comparison with Conventional Interface Methods.Micromachines · 2026
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Adei AbouhaggerDepartment of Functional Materials and Electronics, State Research Institute Centre for Physical Sciences and Technology (FTMC), 02300 Vilnius, Lithuania.ORCID https://orcid.org/0009-0004-0446-5769

Eivydas AndriukonisDepartment of Functional Materials and Electronics, State Research Institute Centre for Physical Sciences and Technology (FTMC), 02300 Vilnius, Lithuania.

Goda GrigorianaiteDepartment of Functional Materials and Electronics, State Research Institute Centre for Physical Sciences and Technology (FTMC), 02300 Vilnius, Lithuania.

Raiane Rodrigues da SilvaDepartment of Functional Materials and Electronics, State Research Institute Centre for Physical Sciences and Technology (FTMC), 02300 Vilnius, Lithuania.

Kamile KasperaviciuteDepartment of Functional Materials and Electronics, State Research Institute Centre for Physical Sciences and Technology (FTMC), 02300 Vilnius, Lithuania.

Arunas StirkeDepartment of Functional Materials and Electronics, State Research Institute Centre for Physical Sciences and Technology (FTMC), 02300 Vilnius, Lithuania.ORCID https://orcid.org/0000-0002-8081-3487

Wanessa C Ma MeloDepartment of Functional Materials and Electronics, State Research Institute Centre for Physical Sciences and Technology (FTMC), 02300 Vilnius, Lithuania.ORCID https://orcid.org/0000-0002-5355-6155

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Microbial biofilms present significant challenges in healthcare due to their persistence and resistance to antimicrobial treatments. Microfluidic technologies offer a promising alternative to traditional static systems for studying biofilm dynamics under physiologically relevant conditions. In this study, we present a poly-(dimethylsiloxane) (PDMS)-free microfluidic platform fabricated using off-stoichiometry thiol-ene (OSTE) resin and cyclic olefin copolymer (COC) substrates. The device features five independent growth chambers and is designed for compatibility with standard laboratory setups. It enables controlled flow conditions, optical transparency for real-time imaging, and integration with antimicrobial testing protocols. Biofilms of

Identifiers

PMID40893319

DOI10.1021/acsomega.5c04643

PMCPMC12392012

What Socratic holds

Textmetadata

LicenceCC BY

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.