Evidence map›Paper›PMID 40893353›Full record

ArticleMaterials today. Bio2025

Light up the mitochondria: Smart tungstate-oligosaccharide nanoplatform orchestrates mitochondrial transfer from M2 macrophages to restore endothelial function for adaptive diabetic wound regeneration.

Xiuhong Huang, Ziling Lin, Mingshu Ruan, Peizhen Huang, Hongmei Ding, Hao Pan, Jiahui Cao, Chunmei Ma, Qianhao Zhao, Wenping Guo and 4 more

Abstract read
In one paragraph

Article in Materials today. Bio, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Review
  3. Therapeutic Potential of Mitochondrial Transplantation with Focus on DBD.International journal of molecular sciences · 2026
    Review
  4. Review
  5. Biofilm-Responsive Nanoplatforms for Infected Wound Reconstruction.International journal of nanomedicine · 2026
    Review
  6. Review
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Xiuhong HuangSchool of Basic Medical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, 510006, China.
Ziling LinDepartment of Hand Surgery and Wound Repair, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, 510405, China.
Mingshu RuanInternational Collage, Guangzhou University of Chinese Medicine, Guangzhou, 510405, China.
Peizhen HuangDepartment of Hand Surgery and Wound Repair, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, 510405, China.
Hongmei DingDepartment of Hand Surgery and Wound Repair, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, 510405, China.
Hao PanSchool of Basic Medical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, 510006, China.
Jiahui CaoSchool of Basic Medical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, 510006, China.
Chunmei MaSchool of Basic Medical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, 510006, China.
Qianhao ZhaoSchool of Basic Medical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, 510006, China.
Wenping GuoSchool of Basic Medical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, 510006, China.
Keke WuSchool of Biomedical Engineering, Affiliated Cancer Hospital & Institute, Guangzhou Medical University, Guangzhou, 511436, China.
Chongkai FangScience and Technology Innovation Center, Guangzhou University of Chinese Medicine, Guangzhou, 510405, China.
Aijun LiuSchool of Basic Medical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, 510006, China.
Liqin ZhengDepartment of Hand Surgery and Wound Repair, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, 510405, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diabetic wound (DW) complications, driven by persistent oxidative stress, unresolved inflammation, and vascular dysfunction, present a critical clinical challenge. Given mitochondria's pivotal role in inflammatory regulation, intercellular mitochondrial transfer emerges as a promising therapeutic target for DW management. In this study, we engineered a ROS/glucose/pH-triple responsive nanoplatform (WOC) via coordination-driven assembly of tungstate anions (WO

Indexed as

AngiogenesisDiabetic woundMacrophageMitochondria transferTungstate-oligosaccharides nanoplatform

Identifiers

PMID40893353
PMCPMC12391290

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.