Evidence map›Paper›PMID 40893366›Full record

ReviewMaterials today. Bio2025

Recent advances in copper sulfide nanoparticles for cancer diagnosis and therapy.

Guangyao Li, Xiang Li, Zhangrong Lou, Junnan Xu, Yiwen Ma, Xiaorui Li, Qiang Liu, Tao Sun

Abstract readReview
In one paragraph

Review in Materials today. Bio, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Engineering Biocompatible Glutathione-Capped CuMaterials (Basel, Switzerland) · 2026
    Article
  5. Article
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Guangyao LiDepartment of Oncology, Cancer Hospital of Dalian University of Technology, Cancer Hospital of China Medical University, Shenyang, 110042, China.
Xiang LiFaculty of Medicine, Dalian University of Technology, Dalian, 116024, China.
Zhangrong LouFaculty of Medicine, Dalian University of Technology, Dalian, 116024, China.
Junnan XuDepartment of Oncology, Cancer Hospital of Dalian University of Technology, Cancer Hospital of China Medical University, Shenyang, 110042, China.
Yiwen MaDepartment of Oncology, Cancer Hospital of Dalian University of Technology, Cancer Hospital of China Medical University, Shenyang, 110042, China.
Xiaorui LiDepartment of Oncology, Cancer Hospital of Dalian University of Technology, Cancer Hospital of China Medical University, Shenyang, 110042, China.
Qiang LiuFaculty of Medicine, Dalian University of Technology, Dalian, 116024, China.
Tao SunDepartment of Oncology, Cancer Hospital of Dalian University of Technology, Cancer Hospital of China Medical University, Shenyang, 110042, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer, a highly heterogeneous and complex disease characterized by multiple genetic and metabolic abnormalities, remains one of the leading causes of death worldwide. Although conventional treatments such as surgery, chemotherapy, and radiotherapy, can mitigate the disease to some extent, their efficacy remains constrained by various factors. In recent years, nanotechnology has emerged as a promising approach for cancer treatment, with copper-based nanomaterials garnering significant attention due to their unique physicochemical properties and favorable biocompatibility. Copper sulfide (CuS) nanomaterials, in particular, have shown great potential as a versatile platform for both diagnosis and therapy, primarily due to their superior photothermal properties. Moreover, copper plays a crucial role in tumorigenesis, progression, and multiple cell death pathways, further highlighting its potential in cancer therapy. This review discusses the metabolic regulation of copper and its diverse roles in tumor biology, examines the applications and recent advances of CuS nanomaterials in cancer therapy, and explores their future potential in cancer diagnosis and treatment.

Indexed as

Copper sulfide nanomaterialsCuproptosisMultimodal combination therapyNanomedicinePhotothermal therapy

Identifiers

PMID40893366
PMCPMC12391698

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.