Evidence map›Paper›PMID 40893372›Full record

ArticleMaterials today. Bio2025

A biomimetic nanoplatform for multimodal imaging-guided therapy of esophageal cancer via synergistic activation of cuproptosis and ferroptosis.

Guodong Ren, Xuewei Wang, Meixu Xu, Ruirui Ma, Yingyu Ma, Sufang Ma, Lihong Li, Lixia Guo, Lili Yan, Boye Zhang and 3 more

Abstract read
In one paragraph

Article in Materials today. Bio, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Guodong RenSchool of Basic Medical Sciences, Shanxi Medical University, Taiyuan, 030001, PR China.
Xuewei WangSchool of Basic Medical Sciences, Shanxi Medical University, Taiyuan, 030001, PR China.
Meixu XuSchool of Basic Medical Sciences, Shanxi Medical University, Taiyuan, 030001, PR China.
Ruirui MaSchool of Basic Medical Sciences, Shanxi Medical University, Taiyuan, 030001, PR China.
Yingyu MaSchool of Basic Medical Sciences, Shanxi Medical University, Taiyuan, 030001, PR China.
Sufang MaSchool of Basic Medical Sciences, Shanxi Medical University, Taiyuan, 030001, PR China.
Lihong LiSchool of Basic Medical Sciences, Shanxi Medical University, Taiyuan, 030001, PR China.
Lixia GuoSchool of Basic Medical Sciences, Shanxi Medical University, Taiyuan, 030001, PR China.
Lili YanSchool of Basic Medical Sciences, Shanxi Medical University, Taiyuan, 030001, PR China.
Boye ZhangSchool of Basic Medical Sciences, Shanxi Medical University, Taiyuan, 030001, PR China.
Haipeng DiaoSchool of Basic Medical Sciences, Shanxi Medical University, Taiyuan, 030001, PR China.
Chengwu ZhangSchool of Basic Medical Sciences, Shanxi Medical University, Taiyuan, 030001, PR China.
Wen LiuSchool of Basic Medical Sciences, Shanxi Medical University, Taiyuan, 030001, PR China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Esophageal cancer (EC) is a gastrointestinal malignancy with high morbidity and mortality. Traditional treatments yield unsatisfactory outcomes and novel intervention strategy is highly demanded. Cuproptosis and ferroptosis are recently defined modes of cell death, which displays promising utility in cancer treatment. However, their application is hindered due to the tumor inherent antioxidation capacity, absence of tumor-targeting, insufficient efficacy of single mode. To address these limitations, one biomimetic nanoplatform (CM@CDs-Cu

Indexed as

Cu9S8CuproptosisEsophageal cancerFerroptosisMultimodal imaging

Identifiers

PMID40893372
PMCPMC12391833

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.