Evidence map›Paper›PMID 40893957›Full record

ArticleACS central science2025

Bidirectional Modification of a

Florian Martin Zielke, Stone Woo, Samuel Kasmali, Allison Volf, Vuong Q Dang, Jake B Bailey, Milan Gembicky, Laura M Bohn, Ryan A Shenvi

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS central science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Florian Martin ZielkeDepartment of Chemistry, Scripps Research, La Jolla, California 92037, United States.
Stone WooDepartment of Chemistry, Scripps Research, La Jolla, California 92037, United States.
Samuel KasmaliDepartment of Chemistry, Scripps Research, La Jolla, California 92037, United States.
Allison VolfGraduate School of Chemical and Biological Sciences, Scripps Research, La Jolla, California 92037, United States.
Vuong Q DangDepartment of Molecular Medicine, The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology, Jupiter, Florida 33458, United States.
Jake B BaileyDepartment of Chemistry and Biochemistry, University of California, San Diego, La Jolla, California 92093, United States.
Milan GembickyDepartment of Chemistry and Biochemistry, University of California, San Diego, La Jolla, California 92093, United States.ORCID https://orcid.org/0000-0002-3898-1612
Laura M BohnGraduate School of Chemical and Biological Sciences, Scripps Research, La Jolla, California 92037, United States.ORCID https://orcid.org/0000-0002-6474-8179
Ryan A ShenviDepartment of Chemistry, Scripps Research, La Jolla, California 92037, United States.ORCID https://orcid.org/0000-0001-8353-6449

Funding

Deconvolution of Galbulimima bark pharmacology through chemical synthesis and target assignmentR01AT012075 · NCCIH · SCRIPPS RESEARCH INSTITUTE, THE · PI Laura M. Bohn, Ryan Ashok Shenvi · 2023 to 2026
$2.4M
Deconvolution of Galbulimima bark pharmacology through chemical synthesis and target assignmentR56AT012075 · NCCIH · SCRIPPS RESEARCH INSTITUTE, THE · PI SHENVI, RYAN ASHOK · 2022 to 2022
$471k
NCCIH NIH HHS R01 AT012075NCCIH NIH HHS R56 AT012075
6 · The paper itself

Abstract

We report a bidirectional diversification and optimization campaign of the newly identified

Identifiers

PMID40893957
PMCPMC12395297

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.