Evidence map›Paper›PMID 40893991›Full record

ArticleJournal of dentistry (Shiraz, Iran)2025

Effect of Nanoemulsion Carbonated Hydroxyapatite-Statin Administration on the Alkaline Phosphatase Level during Orthodontic Relapse in Rats.

Lina Lestia, Niswati Fathmah Rosyida, Yanuarti Retnaningrum, Ananto Ali Alhasyimi

Abstract read
In one paragraph

Article in Journal of dentistry (Shiraz, Iran), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Lina LestiaOrthodontics Resident, Faculty of Dentistry, Universitas Gadjah Mada, Yogyakarta, Indonesia.
Niswati Fathmah RosyidaDept. of Orthodontics, Faculty of Dentistry, Universitas Gadjah Mada, Yogyakarta, Indonesia.
Yanuarti RetnaningrumDept. of Orthodontics, Faculty of Dentistry, Universitas Gadjah Mada, Yogyakarta, Indonesia.
Ananto Ali AlhasyimiDept. of Orthodontics, Faculty of Dentistry, Universitas Gadjah Mada, Yogyakarta, Indonesia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Relapse is acknowledged as a substantial failure after orthodontic correction. As a biomarker of bone formation, alkaline phosphatase (ALP) levels will decline in compressive sites during relapse subsequent to orthodontic tooth displacement. Manipulating alveolar bone remodeling to elevate ALP levels using novel biomaterial is presently regarded as one of the innovative approaches to avert relapse effectively. Purpose: This study aimed to evaluate the effect of carbonated hydroxyapatite (CHA)-statin nanoemulsion on ALP levels in relapsed rats. Materials and Method: In this Results: The average ALP levels between the groups did not differ significantly ( Conclusion: The results indicated that nanoemulsion CHA-statin could elevate ALP levels during orthodontic relapse.

Indexed as

Bone remodelingHealthOrthodonticSimvastatin

Identifiers

PMID40893991
PMCPMC12394739

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.