Evidence map›Paper›PMID 40894768›Full record

ArticlebioRxiv : the preprint server for biology2025

Cortical thickness changes precede high levels of amyloid by at least seven years.

James M Roe, William J Jagust, Susan M Landau, Theresa M Harrison, Håkon Grydeland, Maksim Slivka, José-Luis Alatorre-Warren, Pablo F Garrido, Øystein Sørensen, Edvard O S Grødem and 8 more

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

18 authors.

James M RoeCenter for Lifespan Changes in Brain and Cognition (LCBC), Department of Psychology, University of Oslo, Oslo, Norway.ORCID 0000-0002-8008-902X
William J JagustDepartment of Neuroscience, University of California, Berkeley, Berkeley, CA, USA.
Susan M LandauDepartment of Neuroscience, University of California, Berkeley, Berkeley, CA, USA.
Theresa M HarrisonDepartment of Neuroscience, University of California, Berkeley, Berkeley, CA, USA.ORCID 0000-0002-2036-3496
Håkon GrydelandCenter for Lifespan Changes in Brain and Cognition (LCBC), Department of Psychology, University of Oslo, Oslo, Norway.ORCID 0000-0001-5061-464X
Maksim SlivkaCenter for Lifespan Changes in Brain and Cognition (LCBC), Department of Psychology, University of Oslo, Oslo, Norway.ORCID 0009-0001-7563-250X
José-Luis Alatorre-WarrenCenter for Lifespan Changes in Brain and Cognition (LCBC), Department of Psychology, University of Oslo, Oslo, Norway.ORCID 0000-0002-3638-9957
Pablo F GarridoCenter for Lifespan Changes in Brain and Cognition (LCBC), Department of Psychology, University of Oslo, Oslo, Norway.ORCID 0000-0002-6005-7178
Øystein SørensenCenter for Lifespan Changes in Brain and Cognition (LCBC), Department of Psychology, University of Oslo, Oslo, Norway.ORCID 0000-0003-0724-3542
Edvard O S GrødemCenter for Lifespan Changes in Brain and Cognition (LCBC), Department of Psychology, University of Oslo, Oslo, Norway.ORCID 0000-0003-1915-1872
Tyler J WardDepartment of Neuroscience, University of California, Berkeley, Berkeley, CA, USA.ORCID 0000-0002-4681-8137
Esten H LeonardsenCenter for Lifespan Changes in Brain and Cognition (LCBC), Department of Psychology, University of Oslo, Oslo, Norway.ORCID 0000-0002-5099-116X
Tormod FladbyDepartment of Neurology, Akershus University Hospital, Lørenskog, Norway.ORCID 0000-0002-9984-9797
Atle BjørnerudComputational Radiology and Artificial Intelligence, Department of Radiology and Nuclear Medicine, Oslo University Hospital, Oslo, Norway.ORCID 0000-0002-3486-3141
Kristine B WalhovdCenter for Lifespan Changes in Brain and Cognition (LCBC), Department of Psychology, University of Oslo, Oslo, Norway.ORCID 0000-0003-1918-1123
Anders M FjellCenter for Lifespan Changes in Brain and Cognition (LCBC), Department of Psychology, University of Oslo, Oslo, Norway.ORCID 0000-0003-2502-8774
Didac Vidal-PiñeiroCenter for Lifespan Changes in Brain and Cognition (LCBC), Department of Psychology, University of Oslo, Oslo, Norway.ORCID 0000-0001-9997-9156
Yunpeng WangCenter for Lifespan Changes in Brain and Cognition (LCBC), Department of Psychology, University of Oslo, Oslo, Norway.ORCID 0000-0001-9831-1090

Funding

Alzheimer's Disease Neuroimaging Initiative - SupplementU01AG024904 · NIA · NORTHERN CALIFORNIA INSTITUTE RES &EDUC · PI WEINER, MICHAEL W · 2004 to 2015
$121.0M
NIA NIH HHS U01 AG024904
6 · The paper itself

Abstract

Alzheimer's disease (AD) is now defined based on its underlying brain pathology

Identifiers

PMID40894768
PMCPMC12393315

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.