ArticleiScience2025
Effect of opioid sparing anesthesia with esketamine on PONV in laparoscopic sleeve gastrectomy randomized trial.
Article in iScience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Effect of Different Doses of Esketamine on the Propofol Effect-Site Concentration Required to Suppress Cervical Dilation-Associated Movement During Hysteroscopy: A Prospective, Randomised, Controlled, Parallel-Group Dose-Response Trial.Drug design, development and therapy · 2026Trial
- The role of esketamine in enhancing postoperative recovery and pain management in laparoscopic surgery: a meta-analysis of randomised controlled trials.European journal of anaesthesiology and intensive care · 2026Review
Corrections and comments
- Erratum issued
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Postoperative nausea and vomiting (PONV) remains highly prevalent in laparoscopic sleeve gastrectomy (LSG), with intraoperative opioid use being a key contributing factor. We conducted a prospective, double-blind, randomized trial to compare esketamine-based opioid-sparing anesthesia (OSA) to opioid-based anesthesia in adults undergoing LSG, The primary outcome was the incidence of PONV within 48 h postoperatively. OSA was associated with a significant reduction in the overall incidence of PONV within 48 h, while maintaining comparable analgesic efficacy or postoperative recovery. Additionally, OSA showed clinically significant reductions in both PONV incidence within the first 24 h and severity specifically during the 6-24-h period. Results suggest that OSA is an effective strategy for mitigating PONV following LSG.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.