ReviewBioactive materials2025
Shape memory hydrogels in tissue engineering: Recent advances and challenges.
Review in Bioactive materials, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed.
- Mechano-immunomodulatory biomaterials: From immune mechanosensing to translational design.Bioactive materials · 2026Review
- Intrinsic Correlation between Dynamic Phase Separation and Tunable Multishape Memory Effect in Double-Network Hydrogels.ACS polymers Au · 2026Article
- Ion-triggered reconfigurable hydrogels with salt-enhanced mechanical and swelling properties via network topological adaptation.Nature communications · 2026Article
- From Smart Hydrogel Design to 4D-Printed Scaffolds: Emerging Paradigms in Precision Drug Delivery and Regenerative Wound Therapy.Gels (Basel, Switzerland) · 2026Review
- Collagen-Based Microspheres for Biomedical Applications in Drug Delivery and Tissue Engineering.Biomimetics (Basel, Switzerland) · 2026Review
- Applications of Multifunctional Hydrogel in Tissue Engineering and Regenerative Medicine.MedComm · 2026Review
- Advancing transdermal drug delivery through 4D bioprinting and dynamic skin modelling.Frontiers in drug delivery · 2026Review
- Bioadhesive and hemostatic microneedles integrated with NIR-responsive TiTheranostics · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Shape memory hydrogels (SMHs) have emerged as transformative materials in tissue engineering, owing to their unique ability to recover their original shape after deformation. These hydrogels combine hydrophilicity and elasticity with shape memory capabilities, making them ideal candidates for various biomedical applications. This review examines their innovative design and synthesis, highlighting the physical and biological characteristics that make them well-suited for tissue engineering, such as mechanical properties, biocompatibility, and biodegradability. SMHs have diverse applications in tissue engineering, including bone regeneration, soft tissue reconstruction, and the engineering of vascular and neural tissues. Additionally, they are utilized in smart drug delivery systems and the fabrication of 3D-printed customized implants. Despite these advancements, challenges such as production scalability, optimization of mechanical properties, shape recovery and fixation, controlled degradation, and long-term stability persist. Interdisciplinary approaches are crucial for overcoming these challenges and enhancing their clinical potential. In conclusion, SMHs offer innovative solutions to complex biomedical problems, making them valuable tools for advancing regenerative medicine and improving patient outcomes.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.