Evidence map›Paper›PMID 40895521›Full record

ArticleFrontiers in immunology2025

Ouabain alleviates

Nan Li, Songqiang Huang, Xing Shi, Kuo Lu, Xiu Yu, Chen Qiu, Rongchang Chen

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Nan LiThe Key Laboratory of Shenzhen Respiratory Diseases, Institute of Shenzhen Respiratory Diseases, The First Affiliated Hospital (Shenzhen People's Hospital), School of Medicine, Southern University of Science and Technology, Shenzhen, China.
Songqiang HuangThe Key Laboratory of Shenzhen Respiratory Diseases, Institute of Shenzhen Respiratory Diseases, The First Affiliated Hospital (Shenzhen People's Hospital), School of Medicine, Southern University of Science and Technology, Shenzhen, China.
Xing ShiThe Key Laboratory of Shenzhen Respiratory Diseases, Institute of Shenzhen Respiratory Diseases, The First Affiliated Hospital (Shenzhen People's Hospital), School of Medicine, Southern University of Science and Technology, Shenzhen, China.
Kuo LuThe Key Laboratory of Shenzhen Respiratory Diseases, Institute of Shenzhen Respiratory Diseases, The First Affiliated Hospital (Shenzhen People's Hospital), School of Medicine, Southern University of Science and Technology, Shenzhen, China.
Xiu YuThe Key Laboratory of Shenzhen Respiratory Diseases, Institute of Shenzhen Respiratory Diseases, The First Affiliated Hospital (Shenzhen People's Hospital), School of Medicine, Southern University of Science and Technology, Shenzhen, China.
Chen QiuThe Key Laboratory of Shenzhen Respiratory Diseases, Institute of Shenzhen Respiratory Diseases, The First Affiliated Hospital (Shenzhen People's Hospital), School of Medicine, Southern University of Science and Technology, Shenzhen, China.
Rongchang ChenThe Key Laboratory of Shenzhen Respiratory Diseases, Institute of Shenzhen Respiratory Diseases, The First Affiliated Hospital (Shenzhen People's Hospital), School of Medicine, Southern University of Science and Technology, Shenzhen, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Methods: We investigated the role of ouabain in Results: Ouabain significantly reduced Discussion: These findings indicate that ouabain mitigates

Indexed as

Anti-Inflammatory AgentsInflammasomesMacrophage ActivationMacrophagesMycobacterium abscessusMycobacterium Infections, NontuberculousNLR Family, Pyrin Domain-Containing 3 ProteinOuabainAnimalsCytokinesDisease Models, AnimalHumansMaleMiceMice, Inbred C57BLAnti-Inflammatory AgentsCytokinesInflammasomesNLR Family, Pyrin Domain-Containing 3 ProteinNlrp3 protein, mouseOuabainM1 macrophage polarizationMycobacterium abscessusNLRP3 inflammasome activationouabainpulmonary inflammation

Identifiers

PMID40895521
PMCPMC12394172

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.