Lysozyme-dequalinium encapsulation in a Zn-Fe LDH-chia seed matrix for enhanced antimicrobial dental therapeutics.
Samar M Mahgoub, Abdullah S Alawam, Hassan A Rudayni, Ahmed A Allam, Sahar Abdel Aleem Abdel Aziz, Abdullah A Eweis, Esraa Khaled, Rami Shafei, Fatma Mohamed, Rehab Mahmoud
Article in RSC advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
10 authors.
Samar M MahgoubMaterial Science and Nanotechnology Department, Faculty of Postgraduate Studies for Advanced Sciences (PSAS), Beni-Suef University Beni-Suef 62511 Egypt miramar15@yahoo.com.
Abdullah S AlawamDepartment of Biology, College of Science, Imam Mohammad Ibn Saud Islamic University (IMSIU) Riyadh 11623 Saudi Arabia asalawam@imamu.edu.sa harudayni@imamu.edu.sa aallam@imamu.edu.sa.
Hassan A RudayniDepartment of Biology, College of Science, Imam Mohammad Ibn Saud Islamic University (IMSIU) Riyadh 11623 Saudi Arabia asalawam@imamu.edu.sa harudayni@imamu.edu.sa aallam@imamu.edu.sa.
Ahmed A AllamDepartment of Biology, College of Science, Imam Mohammad Ibn Saud Islamic University (IMSIU) Riyadh 11623 Saudi Arabia asalawam@imamu.edu.sa harudayni@imamu.edu.sa aallam@imamu.edu.sa.
Sahar Abdel Aleem Abdel AzizDepartment of Hygiene, Zoonoses and Epidemiology, Faculty of Veterinary Medicine, Beni-Suef University 62511 Beni-Suef Egypt abdelaziz.sahar@yahoo.com.
Abdullah A EweisDepartment of Botany and Microbiology, Faculty of Science, Beni-Suef University Beni-Suef 62511 Egypt abdullah.ali@science.bsu.edu.eg.
Esraa KhaledBiotechnology Department, Faculty of Post-Graduate Studies for Advanced Sciences, Beni-Suef University Beni-Suef Egypt esraakhaledmahmoud10_pg@psas.bsu.edu.eg.
Rami ShafeiChemistry Department, Faculty of Science, Beni-Suef University Beni-Suef 62511 Egypt rami_shafei@science.bsu.edu.eg rehabkhaled@science.bsu.edu.eg dr_fatma238@yahoo.com.ORCID https://orcid.org/0009-0006-2603-768X
Fatma MohamedChemistry Department, Faculty of Science, Beni-Suef University Beni-Suef 62511 Egypt rami_shafei@science.bsu.edu.eg rehabkhaled@science.bsu.edu.eg dr_fatma238@yahoo.com.
Rehab MahmoudChemistry Department, Faculty of Science, Beni-Suef University Beni-Suef 62511 Egypt rami_shafei@science.bsu.edu.eg rehabkhaled@science.bsu.edu.eg dr_fatma238@yahoo.com.ORCID https://orcid.org/0000-0003-2274-2016
Funding
No grant is acknowledged in the PubMed record.
6 · The paper itself
Abstract
This study developed a lysozyme-dequalinium chloride-loaded Zn-Fe layered double hydroxide (LDH)-chia seed mucilage matrix for enhanced antimicrobial efficacy and sustained drug delivery. The optimized formulation (15% w/v Zn-Fe LDH-chia seed hybrid) achieved encapsulation efficiencies of 93.30 ± 1.92% (lysozyme) and 88.74 ± 1.71% (dequalinium), with a particle size of 153.77 ± 5.79 nm, PDI of 0.18, and zeta potential of +26.44 ± 1.21 mV, ensuring stability and mucoadhesion. Surface morphology, structure, drug loading, and thermostability were confirmed using various techniques.
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.
Lysozyme-dequalinium encapsulation in a Zn-Fe LDH-chia seed matrix for enhanced antimicrobial dental therapeutics. · full record | Socratic