ReviewCureus2025
Impact of Systemic Medications on Oral Health: A Cross-Sectional Study Among Geriatric Patients.
Review in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Evolving aspects of oral care in older adults: a systematic review and Meta-synthesis.BMC oral health · 2026Pooled it
- Oral Self-Care as a Preventive Strategy in Medicated Older Adults: Biological Mechanisms, Genetic Susceptibility, and Public Health Implications.Healthcare (Basel, Switzerland) · 2026Review
- Interdisciplinary Strategies for Improving Oral Health in Older Adults: A Comprehensive Review.Geriatrics (Basel, Switzerland) · 2026Review
- The Intersection of Non-Communicable Chronic Disease and Endodontic Care: A Pilot Retrospective Cross-Sectional Study.Dentistry journal · 2026Article
- Oral lichenoid lesions in association with immunotherapies: a report of two cases and a review of published work.BMC oral health · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The increasing prevalence of chronic diseases in the aging global population has led to widespread use of systemic medications, often resulting in polypharmacy among geriatric patients. While these drugs are essential for managing conditions such as hypertension, diabetes, cardiovascular diseases, and autoimmune disorders, their adverse effects on oral health remain underrecognized and insufficiently studied. This review synthesizes current literature alongside cross-sectional observational data to evaluate the multifaceted impact of commonly prescribed systemic medications on oral health outcomes in elderly populations. Key oral manifestations include xerostomia, gingival overgrowth, mucosal ulcerations, medication-related osteonecrosis of the jaw, bleeding complications, taste alterations, and increased susceptibility to infections. The interplay between age-related physiological changes, polypharmacy, and systemic disease complicates oral care and exacerbates morbidity. Despite the clinical significance, oral side effects are rarely emphasized in pharmacological guidelines, and geriatric-specific data remain limited. The review highlights the need for interdisciplinary collaboration between medical and dental professionals, comprehensive geriatric oral health screening protocols, and increased clinician awareness to improve management and preventive strategies. This integrated approach is essential to enhance the quality of life and oral health outcomes in elderly patients receiving long-term systemic pharmacotherapy.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.