ArticleCureus2025
Efficacy of Platelet-Rich Plasma (PRP) in the Management of Rotator Cuff Tears: A Case Series From a Tertiary Care Center.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo evaluate the short-term tendon healing response to a single ultrasound-guided autologous platelet-rich plasma (PRP) injection in patients aged 25-60 years with clinically and ultrasonographically confirmed unilateral, partial- to full-thickness rotator cuff tears. MATERIALS AND
methodsThis descriptive case series was conducted at the Department of Orthopedic and Spine Surgery, Ghurki Trust Teaching Hospital, Lahore, from April 25 to October 24, 2018. A total of 90 patients aged 25 to 60 years, with clinically and ultrasonographically confirmed partial- and full-thickness rotator cuff tears, were enrolled. Patients with diabetes mellitus, bone infections (e.g., osteomyelitis), or muscular and skeletal dystrophies were excluded. All patients received a single PRP injection administered by the principal investigator. Follow-up assessments were conducted over a 12-week period, and tendon healing was evaluated using ultrasonography. Complete healing was defined as the absence of a tear on follow-up imaging.
resultsNinety patients were included, mean age: 41.46 ± 9.05 years; 61 males (67.78%) and 29 females (32.22%). Most patients (55.56%) were aged 41-60 years, and right shoulder involvement was observed in 56.67% of cases. At 12 weeks, complete tendon healing was noted in 62 patients (68.89%), while 28 patients (31.11%) showed no healing. Stratified analysis revealed no statistically significant association between healing outcomes and age (p = 0.839), gender (p = 0.141), symptom duration (p = 0.900), BMI (p = 0.504), or affected side (p = 0.327).
conclusionPRP therapy was associated with a high rate of tendon healing on ultrasonographic assessment at 12 weeks in patients with partial- to full-thickness rotator cuff tears. While these findings suggest potential short-term structural benefits, they should be interpreted with caution due to the study's descriptive design, lack of a control group, and reliance on ultrasound. Although PRP may be a useful adjunct in conservative management, especially for non-surgical candidates, current evidence supports its role primarily in symptom relief. Larger randomized controlled trials with standardized protocols and functional outcomes are needed to establish its long-term efficacy.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.