Evidence map›Paper›PMID 40896184›Full record

ArticleFrontiers in nutrition2025

Does abnormal weight affect sperm quality? A case-control study based on bioelectrical impedance analysis.

Huang Liu, Xiaoxia Wang, Li Li, Zhiyong Zhu, Hai Lin, Yu Zhou, Houbin Zheng

Abstract read
In one paragraph

Article in Frontiers in nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Huang Liu *Department of Andrology, National Health Commission (NHC) Key Laboratory of Male Reproduction and Genetics, Guangdong Provincial Reproductive Science Institute (Guangdong Provincial Fertility Hospital), Human Sperm Bank of Guangdong Province, Guangzhou, China.
Xiaoxia Wang *Department of Immunology, National Health Commission (NHC) Key Laboratory of Male Reproduction and Genetics, Guangdong Provincial Reproductive Science Institute (Guangdong Provincial Fertility Hospital), Human Sperm Bank of Guangdong Province, Guangzhou, China.
Li Li *Department of Traditional Chinese Medicine, National Health Commission (NHC) Key Laboratory of Male Reproduction and Genetics, Guangdong Provincial Reproductive Science Institute (Guangdong Provincial Fertility Hospital), Human Sperm Bank of Guangdong Province, Guangzhou, China.
Zhiyong ZhuDepartment of Andrology, National Health Commission (NHC) Key Laboratory of Male Reproduction and Genetics, Guangdong Provincial Reproductive Science Institute (Guangdong Provincial Fertility Hospital), Human Sperm Bank of Guangdong Province, Guangzhou, China.
Hai LinDepartment of Andrology, National Health Commission (NHC) Key Laboratory of Male Reproduction and Genetics, Guangdong Provincial Reproductive Science Institute (Guangdong Provincial Fertility Hospital), Human Sperm Bank of Guangdong Province, Guangzhou, China.
Yu ZhouDepartment of Andrology, National Health Commission (NHC) Key Laboratory of Male Reproduction and Genetics, Guangdong Provincial Reproductive Science Institute (Guangdong Provincial Fertility Hospital), Human Sperm Bank of Guangdong Province, Guangzhou, China.
Houbin ZhengDepartment of Andrology, National Health Commission (NHC) Key Laboratory of Male Reproduction and Genetics, Guangdong Provincial Reproductive Science Institute (Guangdong Provincial Fertility Hospital), Human Sperm Bank of Guangdong Province, Guangzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Weight gain can lead to metabolic, circulatory, and systemic changes. Obesity has been confirmed to induce various physical and mental illnesses. The relationship between abnormal weight and male fertility has become a research focus, although the findings regarding their correlation remain controversial. Objective: A case-control study based on bioelectrical impedance analysis was conducted to evaluate the correlation between abnormal body weight and sperm quality and to confirm the degree of impact of abnormal body weight on sperm quality. Methods: A retrospective analysis was conducted of 137 men who underwent fertility assessment at the Guangdong Provincial Reproductive Science Institute (Guangdong Provincial Fertility Hospital) between April 2024 and April 2025. Sperm parameters, body composition parameters, age, height, and other relevant information were extracted and analyzed. One hundred and thirty-seven males were divided into three groups according to their sperm quality: normal sperm group (Group A, Results: The body composition parameters of the different sperm count groups (A, B, and C) were similar and showed no differences. However, there were certain differences in age, height, weight, protein (P), minerals (M), InBody score (IBS), percent body fat (PBF), total body water (TBW), intracellular water (ICW), body fat mass (BFM), body cell mass (BCM), soft lean mass (SLM), and skeletal muscle mass (SMM) between groups AA and BB. They did not follow a linear distribution, and the KMO and Bartlett sphericity tests suggested that they followed a spherical distribution (KMO = 0.775, sig = 0.000), which was related to the presence of sperm. Factor analysis revealed that weight, PBF, height, age, and IBS were the five key influencing factors. After combining height and weight factors, we found the age, IBS, and PBF were more decisive and sensitive than body mass index (BMI). Conclusion: Body composition has a certain impact on sperm quality, especially age, IBS, and PBF, which may be more accurate than BMI. Bioelectrical impedance analysis could effectively assist in the judgment and has the potential to predict sperm parameters.

Indexed as

bioelectrical impedance analysisBMIbody compositionspermatogenesissperm parameters

Identifiers

PMID40896184
PMCPMC12390789

What Socratic holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.