Evidence map›Paper›PMID 40896220›Full record

ArticleFrontiers in psychiatry2025

Enhanced cognitive control following neurofeedback therapy in chronic treatment-resistant PTSD among refugees: a feasibility study.

Mirjana Askovic, Sejla Murdoch, René Mayer-Pelinski, Anna J Watters, James Elhindi, Jorge Aroche, Juri D Kropotov, Anthony W F Harris

Abstract read
In one paragraph

Article in Frontiers in psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Mirjana AskovicNeurofeedback Services, New South Wales Service for the Treatment and Rehabilitation of Torture and Trauma Survivors (STARTTS), Sydney, NSW, Australia.
Sejla MurdochNeurofeedback Services, New South Wales Service for the Treatment and Rehabilitation of Torture and Trauma Survivors (STARTTS), Sydney, NSW, Australia.
René Mayer-PelinskiPractice for Psychotherapy, Ottendorf-Okrilla, Germany.
Anna J WattersBrain Dynamics Centre, Westmead Institute for Medical Research, Westmead, NSW, Australia.
James ElhindiResearch and Education Network, Western Sydney Local Health District, Sydney, NSW, Australia.
Jorge ArocheNeurofeedback Services, New South Wales Service for the Treatment and Rehabilitation of Torture and Trauma Survivors (STARTTS), Sydney, NSW, Australia.
Juri D KropotovNatalia Petrovna (N.P.) Bechtereva Institute of the Human Brain, Russian Academy of Sciences, Saint-Petersburg, Russia.
Anthony W F HarrisSpecialty of Psychiatry, Sydney Medical School, University of Sydney, Westmead, NSW, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Post-traumatic stress disorder (PTSD) is a debilitating condition affecting 3.9% of the global population, with refugee populations experiencing particularly high prevalence rates (23-42%). Cognitive control deficits are a core feature of PTSD and a significant factor in treatment resistance, which affects 25-60% of cases. Methods: This study examined the effects of neurofeedback therapy (NFT) on PTSD symptoms and cognitive control in forty-seven refugees with chronic treatment-resistant PTSD. Pre- and post-treatment assessments included the Harvard Trauma Questionnaire (HTQ), event-related potential (ERP) and behavioural parameters recorded during a cued Go/No-Go task. Over a median of twenty-six sessions across 7 months, clients received individualised NFT integrated with trauma counselling. Post-treatment, clients were categorised into Results: Responders (n=22) demonstrated normalised P3d amplitude, indicative of improved cognitive control. In contrast, non-responders (n=25) exhibited minimal changes in ERP measures. Non-responders showed greater abnormalities in the Slow Positive Wave (SPW) at baseline suggesting more compromised late-stage cognitive processing. Discussion: These findings suggest that NFT can alleviate PTSD symptoms in refugees with chronic treatment-resistant PTSD. Treatment response was associated with a normalisation of the P3d waveform suggestive of enhanced cognitive control. The baseline SPW predicted treatment response. Further research should incorporate randomised controlled trials and larger, multi-centre samples to enhance robustness and generalisability.

Indexed as

chronic post-traumatic stress disordercognitive controlevent-related potentialsneurofeedbackneuromarkersrefugee trauma

Identifiers

PMID40896220
PMCPMC12394473

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.