ArticleFrontiers in psychiatry2025
The value of intellectual structural imbalance in the differentiation of autism spectrum disorder and attention deficit hyperactivity disorder.
Article in Frontiers in psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: The study delves into the intricate task of differentiating intellectual structures among children diagnosed with the high-functioning Autism Spectrum Disorder (HF-ASD), Attention Deficit Hyperactivity Disorder (ADHD), or comorbidity (ASD+ADHD), aiming to assist in their clinical differentiation, with the goal of refining clinical diagnoses and developing targeted therapeutic interventions. Methods: The study included 200 outpatients aged 6.5-13.0 years (total Intelligence Quotient (IQ) 70-130) at the Children's Hospital of Chongqing Medical University, and categorized into HF-ASD (n=91), ADHD (n=47), and comorbidity ASD+ADHD (n=62) groups. We utilized the Chinese Wechsler Intelligence Scale for Children (C-WISC) as the primary assessment tool, supplemented by additional diagnostic measures. Besides, we used SPSS 25.0 to assess the subtest scores and differences. Results: The comorbidity group had lower total IQ than the other two groups ( Conclusion: The peak-valley difference in the ADHD group (~2 standard deviations) was smaller than in the HF-ASD and comorbidity groups (~3 standard deviations), and this characteristic could help differentiate between HF-ASD, ADHD, and both together.
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