ArticleAnimal nutrition (Zhongguo xu mu shou yi xue hui)2025
Indole-3-propionic acid enhances glycolytic myofiber formation in piglets through PI3K-mTOR activation and gut microbiota-driven tryptophan metabolic alteration.
Article in Animal nutrition (Zhongguo xu mu shou yi xue hui), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
5 citing papers in PubMed.
- Breaking the Efflux Barrier: P-Glycoprotein and Emerging Strategies to Overcome Multidrug Resistance in Cancer.Cancers · 2026Review
- Food and Medicine Homology Substances as Potential Modulators of the Gut-Muscle Axis in Animal Meat Quality: A Review.Foods (Basel, Switzerland) · 2026Review
- Propionic Acid Supports the Development of Oocytes Derived from Bovine Early Antral Follicles.Veterinary sciences · 2026Article
- Gut microbiota-derived tryptophan metabolites: molecular mechanisms, nutritional strategies and implications for swine health.Frontiers in veterinary science · 2026Review
- Innovative Approaches to Medical Rehabilitation: Regeneration, Immune Training, Homeostasis, and Microbiome Synergy.International journal of molecular sciences · 2025Review
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Indole-3-propionic acid (IPA) is a metabolite of tryptophan produced by gut bacterial catabolism that has a variety of functions, including anti-inflammatory, free radical scavenging, and regulation of glucose metabolism. The present study evaluated the effects of dietary IPA supplementation on early muscle development in piglets. Twelve healthy Landrace × Rongchang piglets at 30 d of age were randomly divided into control (CON group, 10.78 ± 0.040 kg) and 0.01% IPA (IPA group, 10.80 ± 0.062 kg) for 50 d. The results showed that IPA increased the proportion of glycolytic myofibers significantly in muscle (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.