Evidence map›Paper›PMID 40896579›Full record

ArticleMolecular therapy. Nucleic acids2025

circARHGAP10 as a candidate biomarker and therapeutic target in myotonic dystrophy type 1.

Denisa Baci, Spyros Tastsoglou, Claudia Provenzano, Alessandra Perfetti, Mariapaola Izzo, Mario Lisanti, Svetlana Frolova, Christine Voellenkle, Anna Sofia Tascini, Rosanna Cardani and 4 more

Abstract read
In one paragraph

Article in Molecular therapy. Nucleic acids, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Novel biomarkers for sarcopenia: a narrative review.Journal of orthopaedic surgery and research · 2026
    Review
  4. Article
  5. Implications of circular transcripts in DM1 pathomechanism.Molecular therapy. Nucleic acids · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Denisa BaciMolecular Cardiology Laboratory, IRCCS Policlinico San Donato, San Donato Milanese, Milan 20097, Italy.
Spyros TastsoglouMolecular Cardiology Laboratory, IRCCS Policlinico San Donato, San Donato Milanese, Milan 20097, Italy.
Claudia ProvenzanoInstitute of Biochemistry and Cell Biology, National Research Council, Monterotondo, Rome 00015, Italy.
Alessandra PerfettiMolecular Cardiology Laboratory, IRCCS Policlinico San Donato, San Donato Milanese, Milan 20097, Italy.
Mariapaola IzzoInstitute of Biochemistry and Cell Biology, National Research Council, Monterotondo, Rome 00015, Italy.
Mario LisantiMolecular Cardiology Laboratory, IRCCS Policlinico San Donato, San Donato Milanese, Milan 20097, Italy.
Svetlana FrolovaMolecular Cardiology Laboratory, IRCCS Policlinico San Donato, San Donato Milanese, Milan 20097, Italy.
Christine VoellenkleMolecular Cardiology Laboratory, IRCCS Policlinico San Donato, San Donato Milanese, Milan 20097, Italy.
Anna Sofia TasciniCenter for Omics Sciences, IRCCS Ospedale San Raffaele, 20132 Milan, Italy.
Rosanna CardaniBioCor Biobank, IRCCS Policlinico San Donato, San Donato Milanese, Milan 20097, Italy.
Beatrice CardinaliInstitute of Biochemistry and Cell Biology, National Research Council, Monterotondo, Rome 00015, Italy.
Giovanni MeolaDepartment of Neurorehabilitation Sciences, Casa di Cura Igea, Department of Biomedical Sciences for Health, University of Milan, 20122 Milan, Italy.
Germana FalconeInstitute of Biochemistry and Cell Biology, National Research Council, Monterotondo, Rome 00015, Italy.
Fabio MartelliMolecular Cardiology Laboratory, IRCCS Policlinico San Donato, San Donato Milanese, Milan 20097, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Myotonic dystrophy type 1 (DM1) is a multisystemic disorder caused by expanded CTG repeats in the 3'-UTR of the

Indexed as

alternative splicingbiomarkerscircRNAsDMPKmiR-409-3pMT: Non-coding RNAsmyotonic dystrophy type 1non-coding RNAs

Identifiers

PMID40896579
PMCPMC12395532

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.