Evidence map›Paper›PMID 40897748›Full record

ArticleScientific reports2025

Establishment of Drosophila intestinal cell lines as tools for multiomic screening and deciphering intestinal biology.

Arthur Luhur, Daniel Mariyappa, Peter Bohall, Laura Multini, Morgan Elkins, Andrew C Zelhof

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Arthur Luhur *Drosophila Genomics Resource Center Biology Department, Indiana University, Bloomington, IN, 47405, USA.
Daniel Mariyappa *Drosophila Genomics Resource Center Biology Department, Indiana University, Bloomington, IN, 47405, USA.
Peter BohallDrosophila Genomics Resource Center Biology Department, Indiana University, Bloomington, IN, 47405, USA.
Laura MultiniDrosophila Genomics Resource Center Biology Department, Indiana University, Bloomington, IN, 47405, USA.
Morgan ElkinsDrosophila Genomics Resource Center Biology Department, Indiana University, Bloomington, IN, 47405, USA.
Andrew C ZelhofDrosophila Genomics Resource Center Biology Department, Indiana University, Bloomington, IN, 47405, USA. azelhof@iu.edu.

Funding

Resource Component: Acquisition, maintenance and distribution of Drosophila stocksP40OD018537 · OD · TRUSTEES OF INDIANA UNIVERSITY · PI Annette L. Parks · 2014 to 2026
$13.5M
DROSOPHILA GENOMICS RESOURCE CENTERP40OD010949 · OD · TRUSTEES OF INDIANA UNIVERSITY · PI Andrew Zelhof · 2012 to 2026
$9.4M
NIH HHS P40 OD010949NIH HHS P40OD010949NIH HHS P40 OD018537
6 · The paper itself

Abstract

The Drosophila intestine is a powerful model for stem cell dynamics and epithelial biology, yet no intestinal derived cell lines have been available until now. Here, we describe the establishment of Drosophila intestinal cell lines. The cell lines were derived from the embryonic intestine through specific Ras

Indexed as

DrosophilaDrosophila melanogasterIntestinal MucosaIntestinesAnimalsCell LineCell ProliferationDrosophila ProteinsSignal TransductionDrosophila ProteinsCell lineDrosophilaIntestineSpheroidsTranscriptomics

Identifiers

PMID40897748
PMCPMC12405456

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.