Evidence map›Paper›PMID 40898121›Full record

ArticleBMC psychiatry2025

Anxiety, depression and fear of disease progression among Chinese parents of children with retinoblastoma.

Yilin Yu, Yiyi Feng, Yanping Han, Jie Yang, Xuyang Wen, Xianqun Fan, Jiayan Fan

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yilin Yu *Department of Ophthalmology, Shanghai Ninth People's Hospital, Shanghai JiaoTong University School of Medicine, Shanghai, 200025, P.R. China.
Yiyi Feng *Department of Ophthalmology, Shanghai Ninth People's Hospital, Shanghai JiaoTong University School of Medicine, Shanghai, 200025, P.R. China.
Yanping HanDepartment of Ophthalmology, Shanghai Ninth People's Hospital, Shanghai JiaoTong University School of Medicine, Shanghai, 200025, P.R. China.
Jie YangDepartment of Ophthalmology, Shanghai Ninth People's Hospital, Shanghai JiaoTong University School of Medicine, Shanghai, 200025, P.R. China.
Xuyang WenDepartment of Ophthalmology, Shanghai Ninth People's Hospital, Shanghai JiaoTong University School of Medicine, Shanghai, 200025, P.R. China.
Xianqun FanDepartment of Ophthalmology, Shanghai Ninth People's Hospital, Shanghai JiaoTong University School of Medicine, Shanghai, 200025, P.R. China.
Jiayan FanDepartment of Ophthalmology, Shanghai Ninth People's Hospital, Shanghai JiaoTong University School of Medicine, Shanghai, 200025, P.R. China. qingyang@sjtu.edu.cn.

Funding

Shanghai Key Clinical Specialty, Shanghai Eye Disease Research Center 2022ZZ01003The Fund for Cross research of Shanghai Ninth People's Hospital, Shanghai JiaoTong University School of Medicine JYJC202230The Fund for Excellent Young Scholars of Shanghai Ninth People's Hospital, Shanghai JiaoTong University School of Medicine JYYQ003
6 · The paper itself

Abstract

backgroundRecent studies indicate parents of childhood cancer survivors experience high psychological burden. However, there is limited knowledge regarding the mental health of parents of children with retinoblastoma (RB) in China. Thus, the purpose of this study was to assess anxiety, depression, fear of disease progression (FoP), and family function among parents of children with RB, and to analyze associated factors.

methodsThis cross-sectional study enrolled 151 RB patients and 185 of their parents. Parents completed the Beck Anxiety Inventory (BAI), Beck Depression Inventory (BDI), Fear of Progression Questionnaire-Short Form/Parent version (FoP-Q-SF/PR), and Family APGAR Index to assess the levels of anxiety, depression, FoP, family function. Univariate and multivariate analyses were performed to identify associated factors.

resultsClinically relevant anxiety and depression were reported in 34% and 41% of parents of children with RB. FoP-related dysfunction was observed in 68.1% of parents. More than half of the families (54.9%) exhibited family dysfunction. Anxiety level demonstrated positive correlations with urban residency and BDI scores. The increase in the number of intravenous chemotherapy (IVC), tumor recurrence, urban residency and BAI scores were associated with parental depression levels. Additionally, multivariate analysis included IVC, religious belief, ethnic minority groups and BDI scores as independent risk factors for FoP.

conclusionsAnxiety, depression and FoP represented substantial burdens for parents of children with RB, which were relate to IVC, age at diagnosis, tumor recurrence, place of residence, and education level of parents. Consequently, during treatment of RB, particular attention needs to be paid to the psychological health of parents, psychological interventions should be provided when necessary.

Indexed as

AnxietyDepressionFearParentsRetinal NeoplasmsRetinoblastomaAdultChildChild, PreschoolChinaCross-Sectional StudiesDisease ProgressionEast Asian PeopleFemaleHumansMaleAnxietyDepressionFear of progressionPsychological health of parentsRetinoblastoma

Identifiers

PMID40898121
PMCPMC12403383

What Socratic holds

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LicenceCC BY-NC-ND
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.