Evidence map›Paper›PMID 40898183›Full record

ArticleBMC oral health2025

The osteogenic effect of 3D-printed bone grafting guides in PAOO: a retrospective cohort study.

Han Bao, Yiran Luo, Qingfei He, Yan Jiang, Ling Chen, Yun Wu

Abstract read
In one paragraph

Article in BMC oral health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Han Bao *Stomatological Center, National Regional Medical Center, Binhai Campus of the First Affiliated Hospital, Fujian Medical University, Fuzhou, 350212, China.
Yiran Luo *Stomatological Center, National Regional Medical Center, Binhai Campus of the First Affiliated Hospital, Fujian Medical University, Fuzhou, 350212, China.
Qingfei HeFujian Key Laboratory of Oral Diseases & Fujian Provincial Engineering Research Center of Oral Biomaterial & Stomatological Key Lab of Fujian College and University, School and Hospital of Stomatology, Fujian Medical University, Fuzhou, China.
Yan JiangStomatological Center, National Regional Medical Center, Binhai Campus of the First Affiliated Hospital, Fujian Medical University, Fuzhou, 350212, China.
Ling Chen *Stomatological Center, National Regional Medical Center, Binhai Campus of the First Affiliated Hospital, Fujian Medical University, Fuzhou, 350212, China. 2779704@qq.com.
Yun Wu *Stomatological Center, National Regional Medical Center, Binhai Campus of the First Affiliated Hospital, Fujian Medical University, Fuzhou, 350212, China. 1574316628@qq.com.

Funding

Science and Technology Innovation Joint Foundation of Fujian Provincial 2024Y9136
6 · The paper itself

Abstract

backgroundPeriodontally accelerated osteogenic orthodontics (PAOO) effectively increases alveolar bone volume and broadens orthodontic treatment options. However, bone grafting during PAOO faces challenges such as graft displacement, membrane collapse, and insufficient coronal bone regeneration. This study aimed to evaluate whether 3D-printed digital bone grafting guides could improve graft stability and alveolar bone regeneration compared with conventional PAOO.

methodsIn this retrospective cohort study, 10 patients who underwent PAOO surgery were evaluated. Patients were divided equally into GBG (digital guided bone grafting) and Control groups (conventional PAOO). Cone-beam computed tomography (CBCT) images and periodontal clinical parameters, including probing depth (PD), attachment loss (AL), keratinized gingival width (KW), and gingival biotype, were assessed preoperatively (T0), immediately postoperatively (T1), and at 12 months follow-up (T2). Changes in alveolar bone morphology were analyzed using Mimics software, with data statistically compared using SPSS 25.0.

resultsImmediately postoperatively, the GBG group exhibited significantly greater vertical bone augmentation and horizontal bone augmentation in crown and mid-root areas compared to the control group ([Formula: see text] < 0.05). At the 12-months follow-up, GBG maintained significantly superior vertical bone regeneration and coronal horizontal bone volume, particularly in the coronal third of the alveolar bone ([Formula: see text] < 0.05). Both groups demonstrated significant improvements in KW compared to baseline ([Formula: see text] < 0.05), while PD and AL showed no significant intergroup differences.

conclusionsThe application of 3D-printed bone grafting guides significantly improves graft stability, reduces postoperative bone resorption, and enhances coronal alveolar bone regeneration after PAOO.

Indexed as

Alveolar Ridge AugmentationBone TransplantationOsteogenesisPrinting, Three-DimensionalAdultAlveolar ProcessBone RegenerationCone-Beam Computed TomographyFemaleHumansMaleRetrospective StudiesYoung AdultBone grafting guidesBone regenerationPeriodontally accelerated osteogenic orthodontics

Identifiers

PMID40898183
PMCPMC12406463

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.