ArticlePerioperative medicine (London, England)2025
Endovascular embolization for ruptured intracranial aneurysms: efficacy and effects on oxidative stress levels.
Article in Perioperative medicine (London, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThis study aimed to investigate the efficacy of endovascular embolization in treating ruptured intracranial aneurysms (RIAs).
methodsRIA patients (n = 89) were grouped according to different surgical methods. The control group (n = 42) received aneurysm clipping surgery, whereas the observation group (n = 47) received endovascular embolization. The National Institutes of Health Stroke Scale (NIHSS) was used to assess neurological function pre-treatment and at 7 days post-treatment. Oxidative stress status, including superoxide dismutase (SOD) levels and serum malondialdehyde (MDA) levels, was compared between the two groups pre-treatment and at 7 days post-treatment. Intraoperative bleeding, operative time, and hospitalization time were compared between the two groups. Vascular endothelial function, including von Willebrand factor (vWF), endothelin-1 (ET-1), and nitric oxide (NO), was evaluated pre-treatment and 3 months post-treatment. Postoperative complications and surgical outcomes were observed.
resultsAfter treatment, compared to the control group, the observation group had lower NIHSS scores, higher SOD levels, and lower MDA levels, with statistically significant differences (all P < 0.001); the observation group also had less intraoperative bleeding, shorter operation times, and shorter hospital stays, along with lower vWF and ET-1 levels, higher NO levels, and statistically significant differences (all P < 0.001). The incidence of postoperative complications was lower in the observation group, with a statistically significant difference (P = 0.048). The therapeutic effect was better in the observation group, with a statistically significant difference (P = 0.041).
conclusionCompared with microscopic aneurysm clipping, endovascular embolization offers better efficacy for patients with RIA and causes less vascular endothelial damage.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.