ArticleComprehensive Physiology2025
Influence of Serum Vitamin D on Age-Related Physiological Changes: A Cross-Sectional Study in Middle-Aged Adults.
Article in Comprehensive Physiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Influence of Serum Vitamin D on Age-Related Physiological Changes: A Cross-Sectional Study in Middle-Aged Adults.Comprehensive Physiology · 2025Article
Corrections and comments
- Erratum issued
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe pace of physiological deterioration is variable among living beings. Vitamin D is proven to be one of the crucial yet deficient vitamins. Hypovitaminosis D is often marked by aging, but young adults are also not exempt. Thus, to identify the lacunae and bridge the gap between aging and vitamin D, this study selected the middle-aged age group and their phenotypic aging markers. Physiological changes are gradual and measurable using non-invasive methods, and they contribute to the phenotypic aging markers like BMI, WHR, F%, WS, and HGS. This study hypothesizes that the minute changes in phenotypic markers in young adults, which are prominent during middle age and potentially cause early aging, are influenced by Vitamin D.
methodsThe study is based on a cross-sectional design. Healthy individuals were recruited from the OPD following convenience sampling, and anthropometric and physical assessments were performed. Then, the blood samples were assessed for vitamin D levels. After segregating deficient (< 20 ng/dL), insufficient (20-30 ng/mL), and sufficient (> 20 ng/dL), the comparison was drawn.
resultA frequency analysis of three groups and comparisons among them was made. Association of phenotypic markers with vitamin D was shown.
conclusionThe present study population attempted to establish the hypothesis; however, chronological age can have multicollinearity with all variables, and sample size is a limitation of this study.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.