Evidence mapPaperPMID 40901263Full record

ArticleFrontiers in psychiatry2025

Effects of immersive virtual reality training on the adaptive skills of children and adolescents with high functioning autism spectrum disorder: a mixed-methods pre-post study.

Wenjie Yan, Tianyu Zhai, Yan Li, Jing Chen, Zhixin Sun, Yuxiong Lin, Xiyan Zhang, Yasong Du

Abstract read
In one paragraph

Article in Frontiers in psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Wenjie Yan *Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Tianyu Zhai *Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Yan LiShanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Jing ChenShanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Zhixin SunShanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Yuxiong LinShanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Xiyan ZhangClinical Research Center for Mental Disorders, Shanghai Pudong New Area Mental Health Center, School of Medicine, Tongji University, Shanghai, China.
Yasong DuShanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Autism Spectrum Disorder (ASD) is characterized by social deficits and restricted, repetitive behaviors, with fewer than 10% achieving independent adulthood. Immersive virtual reality (IVR) provides a novel training approach through interactive and realistic environments. This study developed an IVR system to enhance adaptive skills in children and adolescents with high-functioning ASD. Methods: Thirty-three individuals with high-functioning ASD (ages 8-18) were enrolled based on clinical diagnoses confirmed by Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) and Autism Diagnostic Interview-Revised (ADI-R), with an intelligence quotient ≥ 80. The study employed a single-arm, within-subject pre-post design. Participants received weekly one-hour IVR training sessions, requiring 6-10 sessions to complete 36 tasks twice. Primary outcomes included changes in IVR task scores and completion times, while secondary outcomes assessed parent-reported questionnaires - Adaptive Behavior Assessment System-Second Edition (ABAS-II), Autism Behavior Checklist (ABC), and Behavior Rating Inventory of Executive Function (BRIEF) - neuropsychological tests (Go/No-Go, 0-back, 1-back, and emotional face recognition tasks), and semi-structured interviews. Usability was evaluated via self-reported comfort levels, willingness to continue and device-related questions. Generalized Estimating Equation models analyzed changes across all measures. Results: The IVR training demonstrated high usability, with an 87.9% completion rate and no severe adverse effects. Some participants reported mild discomforts, including dizziness (28.6%) and fatigue (25.0%), as well as device-related issues such as unsteady walking (34.5%) and headset discomfort (31.0%). However, comfort levels increased over time (adjusted Conclusion: This pilot study supports IVR training as a feasible and potentially effective training method for improving adaptive skills in children and adolescents with high functioning ASD.

Indexed as

adaptive skillautism spectrum disorderdaily life skillimmersive virtual realityusability

Identifiers

PMID40901263
PMCPMC12399565

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.