ArticleFrontiers in medicine2025
Factors influencing sialorrhea in orally intubated patients: a lasso and logistic regression analysis.
Article in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
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Authors and funding
6 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Objective: To investigate the prevalence of sialorrhea in orally intubated patients and systematically analyze its influencing factors. Methods: A cross-sectional study was conducted from March 15 to 31, 2025, involving 40 tertiary general hospitals across 10 prefecture-level cities in Sichuan Province, including Chengdu, Zigong, and Mianyang. The investigation assessed the current status of sialorrhea in patients undergoing oral endotracheal intubation. Results: A total of 453 questionnaires were collected, of which 440 were valid, yielding an effective response rate of 97.0%. Statistical analysis revealed that the incidence rate of sialorrhea among orally intubated patients was 27.27%. Multivariate logistic regression analysis identified the following as independent risk factors for sialorrhea: Body Mass Index (BMI) (OR = 1.365, 95% CI: 1.217-1.531), Smoking (OR = 8.944, 95% CI: 4.272-18.727), Number of Combined Functional Impairment Systems (OR = 2.844, 95% CI: 1.814-4.460), Combined Oral Disease (OR = 2.578, 95% CI: 1.240-5.359), and Neurological Diseases (OR = 4.040, 95% CI: 1.053-15.507). A restricted cubic spline analysis further demonstrated that when BMI exceeds 22.785, the risk of developing sialorrhea increases significantly. Conclusion: The incidence of sialorrhea in orally intubated patients is at a moderate-to-low level. This condition is closely associated with elevated BMI, smoking, a higher number of combined functional impairments, the presence of oral disease, and underlying nervous system disorders.
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