Evidence map›Paper›PMID 40901675›Full record

ArticleFrontiers in genetics2025

The comparison of the prognostic value of different inflammation-related indicators in patients with oral squamous cell carcinoma.

Aoming Cheng, Kaixiong Wei, Qiaoshi Xu, Chong Wang, Bo Li, Huan Liu, Lirui Zhang, Hanchen Zhou, Yu Huang, Yiming Zhang and 7 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in genetics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Aoming ChengDepartment of Oral and Maxillofacial-Head and Neck Oncology, Beijing Stomatological Hospital, Capital Medical University, Beijing, China.
Kaixiong WeiDepartment of Oral and Maxillofacial-Head and Neck Oncology, Beijing Stomatological Hospital, Capital Medical University, Beijing, China.
Qiaoshi XuDepartment of Oral and Maxillofacial-Head and Neck Oncology, Beijing Stomatological Hospital, Capital Medical University, Beijing, China.
Chong WangDepartment of Oral and Maxillofacial-Head and Neck Oncology, Beijing Stomatological Hospital, Capital Medical University, Beijing, China.
Bo LiDepartment of Oral and Maxillofacial-Head and Neck Oncology, Beijing Stomatological Hospital, Capital Medical University, Beijing, China.
Huan LiuDepartment of Oral and Maxillofacial-Head and Neck Oncology, Beijing Stomatological Hospital, Capital Medical University, Beijing, China.
Lirui ZhangDepartment of Oral and Maxillofacial-Head and Neck Oncology, Beijing Stomatological Hospital, Capital Medical University, Beijing, China.
Hanchen ZhouDepartment of Oral and Maxillofacial-Head and Neck Oncology, Beijing Stomatological Hospital, Capital Medical University, Beijing, China.
Yu HuangDepartment of Oral and Maxillofacial-Head and Neck Oncology, Beijing Stomatological Hospital, Capital Medical University, Beijing, China.
Yiming ZhangDepartment of Oral and Maxillofacial-Head and Neck Oncology, Beijing Stomatological Hospital, Capital Medical University, Beijing, China.
Xue ZhangDepartment of Oral and Maxillofacial-Head and Neck Oncology, Beijing Stomatological Hospital, Capital Medical University, Beijing, China.
Hao WangDepartment of Oral and Maxillofacial-Head and Neck Oncology, Beijing Stomatological Hospital, Capital Medical University, Beijing, China.
Chang LiuDepartment of Oral and Maxillofacial-Head and Neck Oncology, Beijing Stomatological Hospital, Capital Medical University, Beijing, China.
Teng MaDepartment of Stomatology, Beijing Huairou Hospital, Beijing, China.
Jingrui LiDepartment of Clinical Laboratory, Beijing Stomatological Hospital, Capital Medical University, Beijing, China.
Zhengxue HanDepartment of Oral and Maxillofacial-Head and Neck Oncology, Beijing Stomatological Hospital, Capital Medical University, Beijing, China.
Zhien FengDepartment of Oral and Maxillofacial-Head and Neck Oncology, Beijing Stomatological Hospital, Capital Medical University, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: This study aimed to determine the prognostic significance of inflammation markers for patients with oral squamous cell carcinoma (OSCC) and sought to analyze the reasons behind it and its value for clinical guidance. Methods: This study enrolled 624 patients with OSCC who were surgically treated in our hospital. Clinical baseline data and peripheral blood routine/biochemical parameters were collected within 1 week before surgery. The Kaplan-Meier analysis and Cox multifactor regression analysis were performed for statistical analysis. Time-dependent receiver operating characteristic curves (ROC) were used to explore the timeliness of inflammation-related indicators. Results: The Kaplan-Meier analysis revealed that patients with a high-inflammatory trend had significantly shorter overall survival (OS) and disease-free survival (DFS) compared to the patients with a low-inflammatory trend ( Conclusion: ALI and PNI are valuable prognostic indicators in the short term after surgery for young male patients under 60 years old with OSCC.

Indexed as

advanced lung cancer inflammation index (ALI)inflammation-related indicatorsOSCCprognosis predictionprognostic nutritional index (PNI)

Identifiers

PMID40901675
PMCPMC12399640

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.