Evidence map›Paper›PMID 40901945›Full record

ArticleScience advances2025

Synaptic targets of circadian clock neurons influence core clock parameters.

Eva Scholz-Carlson, Aishwarya R Iyer, Aljoscha Nern, John Ewer, Maria P Fernandez

Abstract read
In one paragraph

Article in Science advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Journal of biological rhythms · 2026
    Article
  2. A functional clock in only two dorsal clock neurons is sufficient to restore the basal circadian activity pattern ofProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Eva Scholz-CarlsonDepartment of Biology, Indiana University Bloomington, Bloomington, 47401 IN, USA.ORCID 0000-0002-2349-6585
Aishwarya R IyerDepartment of Biology, Indiana University Bloomington, Bloomington, 47401 IN, USA.ORCID 0000-0002-3607-7021
Aljoscha NernJanelia Research Campus, Howard Hughes Medical Institute, Ashburn, 20147 VA, USA.ORCID 0000-0002-3822-489X
John EwerInstituto de Neurociencia, Universidad de Valparaíso, Valparaíso 2360102, Chile.ORCID 0000-0002-6806-3628
Maria P FernandezDepartment of Biology, Indiana University Bloomington, Bloomington, 47401 IN, USA.ORCID 0000-0002-9261-6114

Funding

Resource Component: Acquisition, maintenance and distribution of Drosophila stocksP40OD018537 · OD · TRUSTEES OF INDIANA UNIVERSITY · PI Annette L. Parks · 2014 to 2026
$13.5M
Micro-Anatomical Mechanisms of Neuronal Circadian Timekeeping, Output, and EntrainmentR01NS118012 · NINDS · TRUSTEES OF INDIANA UNIVERSITY · PI SHAFER, ORIE T · 2021 to 2025
$2.1M
NIH HHS P40 OD018537NINDS NIH HHS R01 NS118012
6 · The paper itself

Abstract

Neuronal connectivity in the circadian clock network is essential for robust endogenous timekeeping. In the

Indexed as

Circadian ClocksDrosophila melanogasterNeuronsSynapsesAnimalsCircadian RhythmDrosophila ProteinsNeuropeptidesSleepTetanus ToxinDrosophila ProteinsNeuropeptidespdf protein, DrosophilaTetanus Toxin

Identifiers

PMID40901945
PMCPMC12407047

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.