Evidence map›Paper›PMID 40902622›Full record

ArticleEndoscopy2025

Adherence to clinical practice guidelines for Management of epithelial precancerous conditions and lesions in the stomach in Europe.

Filipa Fontes, Noa E A Kapteijn, Cesare Hassan, Charlene Deane, Margarida Cristiano, Henrique Fernandes-Mendes, Irina Luzko, Maša Čavlina Sevo, Orlaith Kelly, Gianluca Esposito and 11 more

Abstract readMulticenter Study
In one paragraph

Article in Endoscopy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
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  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Filipa Fontes *Precancerous Lesions and Early Cancer Management Group, Research Center of IPO Porto (CI-IPOP)/CI-IPOP@RISE (Health Research Group), Portuguese Institute of Oncology of Porto (IPO Porto)/Porto Comprehensive Cancer Center (Porto.CCC), Porto, Portugal.
Noa E A Kapteijn *Gastroenterology and Hepatology, Erasmus MC University Medical Center Rotterdam, Rotterdam, Netherlands.
Cesare HassanDigestive Endoscopy Unit, IRCCS Humanitas Research Hospital, Milan, Italy.
Charlene DeaneGastroenerology, Beacon Hospital Research Institute, Dublin, Ireland.
Margarida CristianoGastroenterology, ULS de Coimbra, Coimbra, Portugal.
Henrique Fernandes-MendesGastroenterology, Centro Hospitalar Universitário de Santo António, ULS de Santo António, Porto, Portugal.
Irina LuzkoGastroenterology, Hospital Clinic de Barcelona, Barcelona, Spain.
Maša Čavlina SevoEndoscopy, Gastroenterology and Hepatology, University Hospital Centre Zagreb, Zagreb, Croatia.
Orlaith KellyGastroenerology, Connolly Hospital Blanchardstown, Dublin, Ireland.
Gianluca EspositoMedical-Surgical Sciences and Translational Medicine, Sant'Andrea Hospital, Rome, Italy.ORCID 0000-0002-2242-5048
I Lisanne HolsterGastroenterology, Maasstad Hospital, Rotterdam, Netherlands.
Michiel P J van der HorstPathology, Maasstad Hospital, Rotterdam, Netherlands.
Charlotte F KweldamPathology, Maasstad Hospital, Rotterdam, Netherlands.
Andrei VoiosuGastroenterology, Colentina Clinical Hospital, Bucharest, Romania.ORCID 0000-0001-8579-9314
Ricardo Marcos PintoGastroenterology, Centro Hospitalar Universitário de Santo António, ULS de Santo António, Porto, Portugal.
Nuno AlmeidaGastroenterology, ULS de Coimbra, Coimbra, Portugal.
Colm O'MorainGastroenterology, Tallaght Hospital/Trinity College Dublin, Dublin, United States.
Leticia MoreiraGastroenterology, Hospital Clínic de Barcelona, Barcelona, Spain.
Jan BornscheinMRC Translational Immune Discovery Unit, John Radcliffe Hospital, Oxford, United Kingdom of Great Britain and Northern Ireland.
Manon C W SpaanderGastroenterology and Hepatology, Erasmus MC University Medical Center Rotterdam, Rotterdam, Netherlands.ORCID 0000-0002-9103-9757
Mário Dinis-RibeiroGastroenterology, Instituto Português de Oncologia do Porto, Porto, Portugal.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The first international guideline for managing preneoplastic conditions of the stomach (MAPS I) was published in 2012, followed by an update (MAPS II) in 2019. As adherence to these guidelines remains uncertain, we evaluated adherence by comparing the management of preneoplastic gastric conditions before and after the introduction of MAPS I and II in selected European centers. Methods: Patient data were retrieved from nine endoscopy units in seven European countries during three periods: pre-MAPS I (2010/2011), post-MAPS I (2017/2018), and post-MAPS II (2022/2023). Screening and dyspepsia-related endoscopies were included. Data on endoscopies, histopathology, Helicobacter pylori treatment, and surveillance were collected using a standardized form. Adherence to nine MAPS recommendations was assessed, with improvement defined as a ≥10-percentage point increase in guideline-concordant management. Results: A total of 2426 patients were included. Over the years, most centers (57%) improved in seven of the nine recommendations. Virtual chromoendoscopy use improved in six centers, with four reporting its use in >50% of cases. All centers improved in performing biopsies from the antrum and corpus, five conducted random biopsies in nearly all patients, and four performed these plus a biopsy from the incisura in >90% of cases. Endoscopic scores for patient stratification were rarely used, although five centers improved in histological scoring or intestinal metaplasia subtyping. H. pylori treatment recommendations remained high (71%–100%), and endoscopic surveillance adherence improved in 4/7 centers. Conclusions: Adherence to MAPS guidelines improved in most centers; however, gaps in virtual chromoendoscopy, targeted biopsies, and endoscopic/histopathological scoring remain, potentially affecting surveillance recommendations. This underscores the need for a more tailored approach to enhance implementation.

Indexed as

Guideline AdherencePrecancerous ConditionsStomach NeoplasmsAgedBiopsyEuropeFemaleGastric MucosaGastroscopyHelicobacter InfectionsHelicobacter pyloriHumansMaleMiddle AgedPractice Guidelines as Topic

Identifiers

PMID40902622
PMCPMC12668271

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.