ArticleJournal of advanced research2026
Integrated metabolomic profiling of olive oil, olive mill wastewater, and pomace from Egyptian cultivars based on UHPLC-MS/MS and NMR coupled with chemometrics.
Article in Journal of advanced research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Exploiting the Nutraceutical Potential of Polyphenol-Rich Extra Virgin Olive Oils Through Optimized Sustainable Phenolic Recovery.International journal of molecular sciences · 2026Article
- Emerging Extraction Technologies and Molecular Implications for Greek Olive Products: A Commentary.Molecules (Basel, Switzerland) · 2026Review
- Enhancing agrifood systems with metabolomics: from crop improvement to food quality.Frontiers in molecular biosciences · 2026Review
- Physiological and biochemical variations in different pepper (Capsicum annuum var. conoides) varieties under salt stress.BMC plant biology · 2025Article
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Authors and funding
8 authors.
Funding
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Abstract
introductionOlive oil and their by-products have long been regarded as valuable sources of health-promoting metabolites. Although the composition of olive oil has been widely studied, less attention has been given to olive mill wastewater (OMWW) and pomace across different cultivars (cvs.). The present study provides a comprehensive metabolic profiling of olive oil, OMWW, and pomace derived from 10 Egyptian cvs. using an integrated metabolomics strategy.
methodsA combination of
resultsDistinct phytochemical profiles were revealed across the different olive products. OMWW from "Chemlali black" was found to be particularly rich in phenolics and secoiridoids, while its pomace was characterized by higher levels of unsaturated fatty acids and triterpenoids (e.g., maslinic acid). NMR analyses further distinguished OMWW from pomace based on sugar and organic acid content. Moreover, metabolite-activity relationships were uncovered, with antioxidant capacity being strongly linked to metabolites such as elenolic acid derivatives, tetrahydroxy-methoxy flavanone, hydroxy-octadecadienoic acid, and citric acid. OMWW samples, especially from "Chemlali black", exhibited the most potent antioxidant activity.
conclusionValuable bioactive metabolites were identified in olive oil by-products, supporting their potential use in sustainable, health-promoting applications. "Chemlali black" and "Chemlali green" cvs. are recognized as promising sources for nutraceutical and functional product development. The use of integrated NMR and UHPLC-MS/MS platforms proved effective in differentiating olive matrices and highlighting antioxidant-related metabolic markers.
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