Evidence map›Paper›PMID 40903240›Full record

ReviewJournal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi2025

Advances in malignant hyperthermia: novel insights into heat-induced Ca

Toshiko Yamazawa, Kotaro Oyama, Madoka Suzuki

Abstract readReview
In one paragraph

Review in Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Toshiko YamazawaCore Research Facilities, The Jikei University School of Medicine, 3-25-8 Nishi-Shimbashi, Minato-ku, Tokyo 105-8461, Japan.
Kotaro OyamaTakasaki Institute for Advanced Quantum Science, National Institutes for Quantum Science and Technology, 1233 Watanukimachi, Takasaki-shi, Gunma 370-1292, Japan.
Madoka SuzukiInstitute for Protein Research, The University of Osaka, 3-2 Yamadaoka, Suita, Osaka 565-0871, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Thermoregulation is essential for maintaining homeostasis in mammals under various environmental conditions. Impairment of this function can result in severe conditions, such as fever, heat stroke, and malignant hyperthermia (MH). In this review, we will focus on the role of the type 1 ryanodine receptor (RYR1), a Ca

Indexed as

CalciumCalcium SignalingHot TemperatureMalignant HyperthermiaRyanodine Receptor Calcium Release ChannelAnimalsBody Temperature RegulationExcitation Contraction CouplingHumansMiceMuscle, SkeletalMutationCalciumRyanodine Receptor Calcium Release ChannelCa2+ releasemalignant hyperthermiaryanodine receptorskeletal musclethermal signaling

Identifiers

PMID40903240
PMCPMC12418035

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.