ArticleNature2025
Genetic suppression features ABHD18 as a Barth syndrome therapeutic target.
Abstract read
In one paragraph
Article in Nature, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed.
- Emerging roles of α/β hydrolase domain (ABHD) proteins in S-palmitoylation modification: molecular mechanisms, structural features, and pathological implications.Cellular & molecular biology letters · 2026Review
- De novo synthesis of cardiolipin controls respiratory chain biogenesis in neonatal mouse hearts.EMBO reports · 2026Article
- Article
- Survival and Clinical Progression in Barth Syndrome: Insights From the Barth Syndrome Foundation's Database of 502 Affected Individuals.Journal of inherited metabolic disease · 2026Article
- hUCMSC mitochondrial EVs confer neuroprotection after ischemia by Tom1l2-mediated mitochondrial fusion and Crls1-cardiolipin axis reprogramming.Redox biology · 2026Article
- Saturated cardiolipins are potent disruptors of inner mitochondrial membrane structure and function.bioRxiv : the preprint server for biology · 2026Article
- Effects of Cannabidiol on TAFAZZIN-Deficient B-Lymphoblastoid Cells.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026Article
- Expanding TheCellMap.org to visualize a genome-scale genetic interaction network for a human cell line.bioRxiv : the preprint server for biology · 2026Article
- Cardiolipin remodelling in mitochondrial therapeutics: translational evidence chains from elamipretide to emerging strategies.Frontiers in physiology · 2026Review
- Cardiolipin's multifaceted role in immune response: a focus on interacting proteins.Frontiers in immunology · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
49 authors.
Sanna N Masud *Program in Genetics and Genome Biology, The Hospital for Sick Children, Toronto, Ontario, Canada.
Anchal Srivastava *Scenic Biotech, Amsterdam, The Netherlands.
Patricia MeroProgram in Genetics and Genome Biology, The Hospital for Sick Children, Toronto, Ontario, Canada.
Victoria Saba EchezarretaDepartment of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.
Eve AndersonTransgenic Technology Laboratory, CRUK Scotland Institute, Glasgow, UK.
Lennard van BurenScenic Biotech, Amsterdam, The Netherlands.
Jiarun WeiProgram in Genetics and Genome Biology, The Hospital for Sick Children, Toronto, Ontario, Canada.
David Thomson TaylorProgram in Genetics and Genome Biology, The Hospital for Sick Children, Toronto, Ontario, Canada.
Adrian Granda FariasProgram in Genetics and Genome Biology, The Hospital for Sick Children, Toronto, Ontario, Canada.ORCID 0000-0003-2177-3865
Nicholas MikolajewiczProgram in Genetics and Genome Biology, The Hospital for Sick Children, Toronto, Ontario, Canada.
Angela ShawInstitute of Human Genetics, University of Bonn, Bonn, Germany.
Brandon M MurareanuDepartment of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.ORCID 0000-0002-2517-2517
Michelle LohbihlerDepartment of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.
Olivia Sniezek CarneyDepartment of Genetic Medicine, Johns Hopkins School of Medicine, Baltimore, MD, USA.ORCID 0000-0002-6435-2852
Simon van HeeringenScenic Biotech, Amsterdam, The Netherlands.
Linda ClijstersScenic Biotech, Amsterdam, The Netherlands.ORCID 0000-0002-3118-9702
Olga SizovaProgram in Genetics and Genome Biology, The Hospital for Sick Children, Toronto, Ontario, Canada.
Jeroen van AmeijdeScenic Biotech, Amsterdam, The Netherlands.
Freya NyeTransgenic Technology Laboratory, CRUK Scotland Institute, Glasgow, UK.
Andrea HabsidProgram in Genetics and Genome Biology, The Hospital for Sick Children, Toronto, Ontario, Canada.
Lucy NedyalkovaDonnelly Centre, University of Toronto, Toronto, Ontario, Canada.
Laura McDonaldProgram in Developmental and Stem Cell Biology, The Hospital for Sick Children, Toronto, Ontario, Canada.
Craig SimpsonProgram in Molecular Medicine, The Hospital for Sick Children, Toronto, Ontario, Canada.
Leanne Wybenga-GrootProgram in Molecular Medicine, The Hospital for Sick Children, Toronto, Ontario, Canada.ORCID 0000-0002-7073-9041
Kevin R BrownProgram in Genetics and Genome Biology, The Hospital for Sick Children, Toronto, Ontario, Canada.ORCID 0000-0002-5514-2538
Nhi NhoLundbeck La Jolla Research Center, San Diego, CA, USA.
Radu M SuciuLundbeck La Jolla Research Center, San Diego, CA, USA.
Katherine ChanProgram in Genetics and Genome Biology, The Hospital for Sick Children, Toronto, Ontario, Canada.
Amy H Y TongHong Kong Genome Institute, Hong Kong, China.
Frédéric M VazDepartment of Laboratory Medicine, Amsterdam UMC, Amsterdam, The Netherlands.ORCID 0000-0002-9048-1041
Bastiaan EversScenic Biotech, Amsterdam, The Netherlands.
Robert LesurfProgram in Genetics and Genome Biology, The Hospital for Sick Children, Toronto, Ontario, Canada.ORCID 0000-0001-7095-1491
Tanya PapazDepartment of Pediatrics, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada.
Lauryl M J NutterProgram in Genetics and Genome Biology, The Hospital for Sick Children, Toronto, Ontario, Canada.ORCID 0000-0001-9619-146X
Stephanie ProtzeDepartment of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.ORCID 0000-0002-7993-3780
Maximilian BillmannInstitute of Human Genetics, University of Bonn, Bonn, Germany.
Michael CostanzoDonnelly Centre, University of Toronto, Toronto, Ontario, Canada.ORCID 0000-0002-7906-2604
Brenda J AndrewsDepartment of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.ORCID 0000-0001-6427-6493
Chad L MyersDepartment of Computer Science and Engineering, University of Minnesota, Minneapolis, MN, USA.ORCID 0000-0002-1026-5972
Seema MitalProgram in Genetics and Genome Biology, The Hospital for Sick Children, Toronto, Ontario, Canada.ORCID 0000-0002-7643-4484
Hilary VernonDepartment of Genetic Medicine, Johns Hopkins School of Medicine, Baltimore, MD, USA.
Thijn R BrummelkampScenic Biotech, Amsterdam, The Netherlands.ORCID 0000-0002-3066-7071
Charles BooneDepartment of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.ORCID 0000-0002-3542-6760
Ian C ScottDepartment of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.ORCID 0000-0001-6665-1410
Micah J NiphakisLundbeck La Jolla Research Center, San Diego, CA, USA.
Douglas StrathdeeTransgenic Technology Laboratory, CRUK Scotland Institute, Glasgow, UK.ORCID 0000-0003-2959-4327
Sebastian M B NijmanScenic Biotech, Amsterdam, The Netherlands. sebastian.nijman@proton.me.ORCID 0000-0003-0464-6661
Vincent A BlomenScenic Biotech, Amsterdam, The Netherlands. vincent.blomen@scenicbiotech.com.ORCID 0000-0003-3570-7295
Jason MoffatProgram in Genetics and Genome Biology, The Hospital for Sick Children, Toronto, Ontario, Canada. jason.moffat@sickkids.ca.ORCID 0000-0002-5663-8586
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cardiolipin (CL) is the signature phospholipid of the inner mitochondrial membrane, where it stabilizes electron transport chain protein complexes
Indexed as
Barth SyndromeCardiolipinsMolecular Targeted TherapyMonoacylglycerol LipasesAcyltransferasesAnimalsDisease Models, AnimalFemaleFibroblastsHumansLysophospholipidsMaleMiceMitochondriaMutationPhenotypeAcyltransferasesCardiolipinsLysophospholipidsMonoacylglycerol LipasesmonolysocardiolipinTAFAZZIN protein, humanTranscription Factors
Identifiers
PMID
40903572What Socratic holds
Textmetadata
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.